RCC2 Activators
RCC2 (Regulator of Chromosome Condensation 2) activators represent a class of compounds that have gained attention for their specific role in the regulation of the cell cycle and chromatin condensation. RCC2 is a protein that plays a pivotal part in cell division, acting as a guanine nucleotide exchange factor for the small GTPase Ran. Its activation is integral to the progression of mitosis, where it modulates the nucleocytoplasmic transport of key regulatory molecules and helps orchestrate the orderly distribution of genetic material. The class of RCC2 activators encompasses molecules and compounds that are capable of enhancing the activity of RCC2, ultimately leading to a more efficient and precise cell division process.
RCC2 activators operate at a fundamental level of cellular regulation. By enhancing the function of RCC2, these compounds can influence the accuracy of chromosome segregation during mitosis. This, in turn, has broader implications for cell proliferation, genome stability, and overall cell health. RCC2 activators may find applications in various fields of research, ranging from cell biology to oncology, as understanding the precise control of cell division and chromatin organization is critical for uncovering mechanisms.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tozasertib | 639089-54-6 | sc-358750 sc-358750A | 25 mg 50 mg | $62.00 $87.00 | 4 | |
An Aurora kinase inhibitor that interferes with mitotic spindle formation, affecting the pathways related to LMOD2 activation in actin dynamics. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
An inhibitor of protein phosphatases, indirectly influencing LMOD2 activation by altering the phosphorylation status of proteins, potentially impacting its actin-modulating function. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
A microtubule-targeting agent that disrupts microtubules and spindle formation, indirectly impacting LMOD2 activation by interfering with the microtubule-associated processes it is involved in. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
A DNA damaging agent known for its impact on DNA damage checkpoints and associated pathways, potentially affecting LMOD2 activation through its influence on the DNA damage response pathways it interacts with. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
An HDAC inhibitor influencing gene expression and chromatin structure, potentially impacting LMOD2 activation by modulating chromatin accessibility and gene expression related to actin regulation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can indirectly affect LMOD2 activation by influencing the mTOR pathway, which is involved in cell growth and actin cytoskeleton dynamics, where LMOD2 functions. | ||||||
AZD7762 | 860352-01-8 | sc-364423 | 2 mg | $107.00 | ||
A Chk inhibitor that can alter the DNA damage response pathways, indirectly impacting LMOD2 activation by affecting the DNA damage checkpoint mechanisms LMOD2 might be involved in. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A cell cycle checkpoint inhibitor that can indirectly influence LMOD2 activation by disrupting cell cycle checkpoints, potentially affecting the regulation of actin dynamics, where LMOD2 plays a role. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
An apoptosis inducer that impacts various cellular processes, including actin dynamics, which may indirectly influence LMOD2 activation by modulating mechanisms related to actin cytoskeleton regulation. | ||||||