RBM33 Inhibitors
RBM33 inhibitors represent a category of chemical compounds designed to interact with the RBM33 protein, a component of cellular machinery that may play a role in various biological processes. RBM33, or RNA-binding motif protein 33, is a protein encoded by the RBM33 gene in humans. It is characterized by the presence of RNA-binding domains, which are indicative of its potential involvement in RNA processing or regulation. The precise biological function of RBM33 remains an active area of research, and consequently, the inhibitors targeting this protein are of significant interest in the scientific community. These inhibitors are structured to bind specifically to RBM33, aiming to modulate its activity within the cell.
The development and study of RBM33 inhibitors involve intricate chemical design to ensure specificity and efficacy in binding to the RBM33 protein. The chemical structures of these inhibitors are often complex, tailored to engage with the unique features of the protein's active site or RNA-binding domains. Researchers utilize a variety of techniques, such as high-throughput screening, computational modeling, and structure-activity relationship studies, to identify and optimize these molecules. The identification of these inhibitors typically requires a deep understanding of the protein's structure and the chemical interactions that can occur between the protein and potential inhibitory compounds. RBM33 inhibitors are synthesized through a series of chemical reactions, and their interactions with RBM33 are usually evaluated using biochemical assays that can assess the binding affinity and the resultant modulation of the protein's activity.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3K). if it were involved in pathways regulated by PI3K, wortmannin would lead to decreased activity of RBM33 by disrupting downstream signaling events. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
This compound is a specific inhibitor of PI3K, similar to wortmannin. If RBM33 function is related to PI3K signaling, LY294002 would inhibit the pathway, potentially diminishing RBM33 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a selective inhibitor of mitogen-activated protein kinase kinase (MEK), which is a part of the MAPK/ERK pathway. If RBM33 operates downstream of this pathway, inhibition by PD98059 might reduce RBM33 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 specifically inhibits p38 MAP kinase. If RBM33 is activated by p38 MAPK signaling, inhibition by SB203580 would indirectly decrease RBM33 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), SP600125 would indirectly affect RBM33 if it is linked with JNK signaling, leading to a reduction in RBM33 functional activity. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts protein trafficking by inhibiting ADP-ribosylation factor (ARF), a GTPase involved in vesicle formation. If RBM33 is dependent on proper trafficking for its function, Brefeldin A would decrease its activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an inhibitor of the mechanistic target of rapamycin (mTOR). If RBM33 is a part of pathways influenced by mTOR, rapamycin could lead to a reduction in RBM33 activity. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Cyclosporin A inhibits calcineurin, thus affecting T-cell activation. If RBM33 is implicated in T-cell signaling, Cyclosporin A would indirectly inhibit RBM33 activity. | ||||||
Ro 31-8220 | 138489-18-6 | sc-200619 sc-200619A | 1 mg 5 mg | $90.00 $240.00 | 17 | |
Ro-31-8220 is a potent protein kinase C (PKC) inhibitor. If RBM33's functional activity is regulated by PKC signaling, this inhibitor would lead to a decrease in RBM33 activity. | ||||||
ZM 336372 | 208260-29-1 | sc-202857 | 1 mg | $46.00 | 2 | |
ZM 336372 is an inhibitor of RAF kinases. If RBM33 is involved in RAF/MAPK signaling, inhibition by ZM 336372 could reduce RBM33 activity. | ||||||