RBM33 inhibitors represent a category of chemical compounds designed to interact with the RBM33 protein, a component of cellular machinery that may play a role in various biological processes. RBM33, or RNA-binding motif protein 33, is a protein encoded by the RBM33 gene in humans. It is characterized by the presence of RNA-binding domains, which are indicative of its potential involvement in RNA processing or regulation. The precise biological function of RBM33 remains an active area of research, and consequently, the inhibitors targeting this protein are of significant interest in the scientific community. These inhibitors are structured to bind specifically to RBM33, aiming to modulate its activity within the cell.
The development and study of RBM33 inhibitors involve intricate chemical design to ensure specificity and efficacy in binding to the RBM33 protein. The chemical structures of these inhibitors are often complex, tailored to engage with the unique features of the protein's active site or RNA-binding domains. Researchers utilize a variety of techniques, such as high-throughput screening, computational modeling, and structure-activity relationship studies, to identify and optimize these molecules. The identification of these inhibitors typically requires a deep understanding of the protein's structure and the chemical interactions that can occur between the protein and potential inhibitory compounds. RBM33 inhibitors are synthesized through a series of chemical reactions, and their interactions with RBM33 are usually evaluated using biochemical assays that can assess the binding affinity and the resultant modulation of the protein's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is another selective inhibitor of MEK. By blocking MEK1/2, U0126 could lead to decreased activity of RBM33 if it is part of the ERK pathway. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. If RBM33 is involved in the EGFR signaling pathway, the inhibition of EGFR by gefitinib could lead to decreased RBM33 activity. | ||||||