Raver1 Activators
Raver1 Activators encompasses a diverse group of compounds known for their capacity to modulate the activity of the Raver1 protein. Raver1, identified as a ribonucleoprotein with PTB-binding capabilities, plays a crucial role in mRNA binding and the regulation of alternative mRNA splicing. Chemicals falling under the umbrella of Raver1 activators interact with various cellular mechanisms to influence the protein directly or indirectly. Forskolin is recognized for its ability to activate adenylyl cyclase, leading to an elevation in intracellular cyclic AMP (cAMP) levels. This, in turn, sets off a cascade of downstream signaling events, impacting cellular processes such as gene expression and protein synthesis, and potentially activating Raver1 through cAMP-dependent pathways.
As Raver1 is implicated in mRNA splicing, the cellular stress induced by Thapsigargin may lead to alterations in alternative splicing patterns, indirectly impacting Raver1 activity. These Raver1 activators, with their distinct mechanisms of action, provide valuable tools for researchers seeking to understand the intricate regulatory networks governing RNA processing and splicing within the cellular milieu. The exploration of such compounds sheds light on the nuanced ways in which Raver1 can be modulated, contributing to the broader understanding of cellular processes underpinning gene expression and RNA regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $26.00 $34.00 | 20 | |
Antibiotic known to interact with RNA structures, potentially activating the binding activity of Raver1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, leading to increased cAMP levels, which may indirectly activate Raver1 through cAMP-dependent pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Epigenetic modifier that activates DNA demethylation, potentially activating Raver1 through epigenetic regulation. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Induces endoplasmic reticulum stress, potentially activating Raver1 through cellular stress response pathways. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Calcium channel blocker that activates ion channels, potentially activating Raver1 through calcium-dependent signaling pathways. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
Inhibitor of glycolysis, affecting cellular metabolism, which may indirectly activate Raver1 activity through metabolic regulation. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that affects the ubiquitin/proteasome pathway, potentially activating Raver1 protein levels. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
Cell-permeable analog of cAMP, modulating second messenger pathways that could indirectly activate Raver1 activity. | ||||||
Pertussis Toxin (islet-activating protein) | 70323-44-3 | sc-200837 | 50 µg | $442.00 | 3 | |
Inhibits G-protein activity, potentially activating Raver1 through G-protein-coupled receptor signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activator of protein kinase C, influencing MAP kinase pathways that could indirectly activate Raver1 activity. | ||||||