Rab11-FIP3 Activators
Rab11-FIP3 activators represent a class of proteins that play a crucial role in regulating intracellular membrane trafficking and vesicle transport within eukaryotic cells. These activators are specifically involved in the activation of Rab11-FIP3 (Rab11 Family-Interacting Protein 3), a member of the Rab GTPase family. Rab GTPases are known for their pivotal function in coordinating vesicular traffic, and Rab11-FIP3 activators, as the name suggests, are proteins that modulate the activity of Rab11-FIP3, influencing various cellular processes.
Rab11-FIP3 activators are responsible for stimulating the GTPase activity of Rab11-FIP3. This interaction is a central mechanism in the regulation of endocytic recycling and intracellular membrane traffic. By promoting the activation of Rab11-FIP3, these proteins participate in the sorting and trafficking of endocytic vesicles, which are essential for the proper function of cells. The activity of Rab11-FIP3 activators is tightly regulated, and their precise role in intracellular transport processes varies across different cell types and cellular contexts. In summary, Rab11-FIP3 activators are a class of proteins that facilitate intracellular membrane trafficking by influencing the activation of Rab11-FIP3, contributing to fundamental cellular processes related to vesicle transport, endocytic recycling, and organelle dynamics.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Indirectly modulates Rab11-FIP3 activity by inhibiting protein phosphatases, potentially leading to increased phosphorylation and activation of Rab11-FIP3. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Serves as an activator of protein kinase C (PKC), indirectly impacting Rab11-FIP3 by triggering PKC-mediated pathways that may enhance its activation. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Directly impacts Rab11-FIP3 by altering actin dynamics, which indirectly influences its role in vesicle trafficking. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Directly affects Rab11-FIP3 by modulating its stability and activity through the regulation of protein degradation pathways. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Directly influences Rab11-FIP3 by disrupting the structure and function of the Golgi apparatus, leading to alterations in membrane trafficking pathways involving Rab11-FIP3. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Directly inhibits mTOR, a regulator of cellular processes, indirectly influencing Rab11-FIP3 activation. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Directly disrupts actin polymerization, affecting Rab11-FIP3 by modulating cytoskeletal dynamics and vesicle trafficking pathways. | ||||||
Autophagy Inhibitor, 3-MA | 5142-23-4 | sc-205596 sc-205596A | 50 mg 500 mg | $65.00 $261.00 | 113 | |
Directly inhibits autophagy, which directly influences Rab11-FIP3 by altering cellular processes associated with autophagy, potentially affecting its activation. | ||||||