R3HDML Inhibitors
The "R3H domain containing like" protein, which can be abbreviated as R3HDL, is characterized by the presence of an R3H domain. The R3H domain is a conserved sequence motif found in a variety of proteins and is known to mediate protein-DNA, protein-RNA, or protein-protein interactions. Proteins with this domain are involved in a plethora of cellular processes, including but not limited to RNA binding, RNA metabolism, DNA repair, and gene regulation.This suggests a potential role for R3HDL in processes such as the regulation of mRNA stability, the modulation of transcription, and the maintenance of genome integrity. For example, R3H domain proteins may participate in the recognition and processing of mRNA precursors, or in the regulation of mRNA decay, thus influencing gene expression post-transcriptionally.Given the pivotal role of RNA in cellular function and the involvement of R3H domain proteins in RNA metabolism, mutations or dysregulation of R3HDL could potentially be implicated in a range of diseases, especially those related to aberrant gene expression.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Binds to DNA at the transcription initiation complex, inhibiting RNA polymerase and potentially decreasing R3H domain protein expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Inhibits transcription by affecting the activity of RNA polymerase II, potentially leading to reduced expression of R3H domain proteins. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Specifically inhibits RNA polymerase II, which could lead to decreased transcription of R3H domain-containing genes. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Interferes with DNA replication and transcription by intercalating into DNA, which may downregulate R3H domain protein expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to GC-rich sequences in DNA, preventing transcription factor binding and potentially decreasing R3H domain protein expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferase, leading to DNA demethylation and potentially altered expression of R3H domain proteins. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylase, affecting chromatin structure and potentially gene expression, including R3H domain proteins. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits RNA polymerase II transcription elongation, which could reduce R3H domain protein expression. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $317.00 | ||
Inhibits cyclin-dependent kinases, leading to the suppression of RNA polymerase II-mediated transcription. | ||||||
I-CBP112 | 1640282-31-0 | sc-507494 | 25 mg | $400.00 | ||
A small molecule designed to inhibit CBP/p300, which could alter gene expression patterns including R3H domain proteins. | ||||||