Molecular structure of I-CBP112, CAS Number: 1640282-31-0
I-CBP112 (CAS 1640282-31-0)
CAS Number:
1640282-31-0
Molecular Weight:
468.59
Molecular Formula:
C27H36N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
I-CBP112 (CAS 1640282-31-0) References
- Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112. | Zucconi, BE., et al. 2016. Biochemistry. 55: 3727-34. PMID: 27332697
- Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP. | Zucconi, BE., et al. 2019. Biochemistry. 58: 2133-2143. PMID: 30924641
- Polydatin and I-CBP112 protects early bovine embryo against nicotinamide-induced mitochondrial dysfunction. | Yuan, YG., et al. 2019. Theriogenology. 134: 1-10. PMID: 31108431
- Nicotinamide-induced mouse embryo developmental defect rescued by resveratrol and I-CBP112. | Yuan, YG., et al. 2020. Mol Reprod Dev. 87: 1009-1017. PMID: 32818292
- A Chemo-Genomic Approach Identifies Diverse Epigenetic Therapeutic Vulnerabilities in MYCN-Amplified Neuroblastoma. | Krstic, A., et al. 2021. Front Cell Dev Biol. 9: 612518. PMID: 33968920
- Pharmacological targeting of Sam68 functions in colorectal cancer stem cells. | Masibag, AN., et al. 2021. iScience. 24: 103442. PMID: 34877499
- Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents. | Chen, Q., et al. 2022. Theranostics. 12: 4935-4948. PMID: 35836809
- EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs. | Rubio, K., et al. 2023. Int J Mol Sci. 24: PMID: 37569677
- HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis. | Emmons, MF., et al. 2023. Nat Commun. 14: 7759. PMID: 38030596
- EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells. | Huttunen, J., et al. 2024. Cell Mol Life Sci. 81: 160. PMID: 38564048
Inhibitor of:
Abi-2, ACF, Ada1, BAF170, BAZ2B, C1orf43, DPF3, EG628705, Gm98, HIGD1C, Histone cluster 1 H2BD, Histone cluster 1 H4I, Histone cluster 1 H4M, Histone H1B, Histone H2A.Bbd, Iws1, KCNH1, Krox-8, KTI12, Lce1g, Med17, MSL3L2, p300, PHF3, PLAG1, R3HDML, Snf2, SOHLH2, TADA2B, TADA2L, TAFII-18, TGIF2, WCRF, ZBTB43, ZFP2, and ZNF143.Activator of:
BAF, Brpf1, Histone cluster 1 H3B, Histone cluster 4 H4, INO80B, KIAA2026_9930021J03Rik, and SA-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
I-CBP112, 25 mg | sc-507494 | 25 mg | $400.00 |