PRRC1 Inhibitors
PRRC1 Inhibitors encompass a variety of chemical compounds that target specific signaling pathways and cellular processes to achieve the inhibition of PRRC1's functional activity. Kinase inhibitors play a significant role by affecting phosphorylation states, a crucial post-translational modification that is likely pivotal for PRRC1 function. For instance, inhibition of protein kinase C and kinase activities within the PI3K-AKT and ERK pathways can hinder the phosphorylation cascade that may regulate PRRC1 activity. On a broader scale, compounds that disrupt the MAPK signaling network, such as JNK and p38 MAP kinase inhibitors, can prevent the activation of transcription factors and proteins that are integral to PRRC1's role in the cell, thereby mitigating its action.
Additionally, there are inhibitors that target key regulators of protein synthesis and cellular growth, such as mTOR, which could potentially impede the production or activity of PRRC1 by altering downstream signaling events. Compounds that inhibit MEK or Src family kinases also contribute to the modulation of PRRC1 activity by affecting the signaling pathways that control its phosphorylation and function. Furthermore, antagonists of G-proteins and inhibitors of the Rho-associated protein kinase (ROCK) can alter cellular processes such as GPCR signaling and actin cytoskeleton dynamics.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent kinase inhibitor that affects various signaling pathways, including those that may regulate the phosphorylation state and activity of PRRC1. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
A protein kinase C inhibitor that can impact the phosphorylation of proteins involved in the same pathways as PRRC1, leading to its functional inhibition. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A phosphoinositide 3-kinase inhibitor that disrupts PI3K-AKT signaling, which could be necessary for PRRC1-mediated processes, resulting in its inhibition. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An extracellular signal-regulated kinase inhibitor that can alter ERK pathway signaling, potentially reducing PRRC1 activity if it is linked to this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK) that could prevent activation of transcription factors and proteins associated with PRRC1, thereby inhibiting its function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that prevents AKT activation, possibly affecting PRRC1 activity by modifying downstream signaling events. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAP kinase inhibitor, which may impede signaling cascades that influence the functional state of PRRC1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can suppress the mTOR pathway, potentially impacting the synthesis and activity of proteins like PRRC1 that are involved in related cellular processes. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor that blocks the MEK1/2-ERK1/2 signaling pathway, potentially downregulating PRRC1 activity if it is modulated by this pathway. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
A Src family kinase inhibitor that may disrupt signaling pathways that control the phosphorylation and activity of proteins such as PRRC1. | ||||||