PRR21 Inhibitors would refer to a conceptual class of chemical agents crafted to selectively obstruct the activity of the protein encoded by the PRR21 gene. If PRR21 were similar to other proline-rich proteins, its function might include involvement in various cellular processes like signal transduction, cell adhesion, or the regulation of transcription. Inhibitors would target the specific domains or motifs within the PRR21 protein that are crucial for its interaction with other cellular components, such as binding partners or DNA elements, to inhibit its function.
The design of PRR21 Inhibitors would encompass a meticulous investigation into the protein's structure-function relationship. This would involve identifying the active sites or binding interfaces via methods such as crystallography, NMR spectroscopy, or cryo-electron microscopy. Once target sites are determined, small molecules could be synthesized to specifically bind to these regions, thereby inhibiting PRR21's activity. These inhibitors could act by competing with natural ligands or substrates, by allosterically modifying the protein's structure, or by covalently modifying key residues essential for the protein's function. The utilization of these PRR21 inhibitors would illuminate PRR21's role in cellular contexts. By observing the biological outcomes that ensue following the inhibition of PRR21, insights into the protein's function and its importance in cellular physiology could be gained. For instance, should PRR21 be implicated in the regulation of gene expression, its inhibition might result in altered transcriptional profiles, which could then be studied to unravel the regulatory networks within the cell. The study of PRR21 inhibitors could also contribute to the foundational knowledge of proline-rich proteins and their interactions within the cell, revealing new dimensions of cell biology and protein dynamics. It's important to reiterate that such inhibitors would represent powerful tools in basic research, aiding in the dissection of complex biological systems.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Might regulate gene expression by activating nuclear retinoic acid receptors which bind to DNA response elements. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor could lead to demethylation of DNA, potentially increasing gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor that may upregulate gene expression by altering histone acetylation and chromatin structure. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Elevates intracellular cAMP, which can activate PKA and modulate transcription factor activity to increase gene expression. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Through estrogen receptors, it can modulate the transcription of target genes via estrogen response elements. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
This HDAC inhibitor can enhance histone acetylation, leading to a more open chromatin state and potentially increased gene expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Can act on glucocorticoid receptors, influencing gene transcription through glucocorticoid response elements in DNA. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Affects gene expression by influencing epigenetic pathways, potentially altering DNA methylation and histone acetylation. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
Used as a solvent, DMSO can also influence gene expression through its effects on cellular processes. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Induces ER stress and activates the unfolded protein response, which can alter gene expression patterns. | ||||||