MAIR-II Activators are a diverse array of chemical compounds that, through their interaction with various biochemical pathways, serve to enhance the functionality of MAIR-II, a protein involved in immune cell regulation. Benzyl benzoate and Resolvin D1 play roles in modulating G protein-coupled receptor signaling, which could indirectly potentiate the activity of MAIR-II by influencing immune responses in which MAIR-II is involved. Anandamide, via the CB2 receptor, and PGE2, through its EP receptors, may augment the inhibitory signaling of MAIR-II, contributing to an anti-inflammatory state. Similarly, the action of Platelet-activating factor and Adenosine on their respective receptors can modulate immune cell pathways to amplify MAIR-II's regulatory effects. Lipoxin A4, by engaging with the ALX/FPR2 receptor, and NAD+, through its influence onMAIR-II Activators are chemical compounds that indirectly augment the functional activity of MAIR-II, a protein implicated in immune cell signaling.
Benzyl benzoate, which serves as a ligand for GPR50, may indirectly promote MAIR-II signaling by modulating GPR50 activity, potentially influencing immune cell responses that involve MAIR-II. Similarly, Resolvin D1 and Lipoxin A4, both acting on the ALX/FPR2 receptor, can enhance the anti-inflammatory signaling pathways where MAIR-II is active, contributing to the suppression of inflammation. Anandamide, which interacts with cannabinoid receptors, and PGE2, targeting EP receptors, are also capable of enhancing MAIR-II mediated actions in myeloid cells, reinforcing the protein's role in immune regulation. Platelet-activating factor and Adenosine, each acting through their specific receptors, can modulate immune responses in a manner that may potentiate MAIR-II's inhibitory effects, thereby dampening inflammation.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Sodium Chloride | 7647-14-5 | sc-203274 sc-203274A sc-203274B sc-203274C | 500 g 2 kg 5 kg 10 kg | $18.00 $23.00 $35.00 $65.00 | 15 | |
Enhances Pronase activity by optimizing ionic strength, crucial for maintaining its structural integrity and enzymatic efficiency. | ||||||
Calcium chloride anhydrous | 10043-52-4 | sc-207392 sc-207392A | 100 g 500 g | $65.00 $262.00 | 1 | |
Stabilizes Pronase structure by binding at specific sites, promoting a conformation favorable for substrate binding and catalysis. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $45.00 $68.00 $160.00 $240.00 $410.00 | 3 | |
Provides magnesium ions as cofactors, essential for proper folding and structural integrity of Pronase. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Supplies zinc ions for structural stabilization of Pronase, aiding in maintaining the active site geometry for effective enzymatic action. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2) interacts with its EP receptors on immune cells, modulating immune responses. PGE2 signaling could indirectly increase the inhibitory activity of MAIR-II on myeloid cells, leading to a dampened inflammatory response. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Adenosine interacts with adenosine receptors, which are involved in anti-inflammatory responses. Activation of these receptors could potentially enhance the activity of MAIR-II by promoting signaling pathways that favor immune suppression. | ||||||
Lipoxin A4 | 89663-86-5 | sc-201060 sc-201060A sc-201060B sc-201060C | 25 µg 50 µg 100 µg 250 µg | $342.00 $485.00 $923.00 $2025.00 | 2 | |
Lipoxin A4 is an anti-inflammatory eicosanoid that binds to the ALX/FPR2 receptor. It may enhance MAIR-II's activity by facilitating the anti-inflammatory signaling pathways in which MAIR-II participates, thereby contributing to the resolution of inflammation. | ||||||
Glycerol | 56-81-5 | sc-29095A sc-29095 | 100 ml 1 L | $55.00 $150.00 | 12 | |
Acts as a stabilizing agent, enhancing Pronase stability and activity by affecting the hydration shell and microenvironment. | ||||||
Urea | 57-13-6 | sc-29114 sc-29114A sc-29114B | 1 kg 2 kg 5 kg | $30.00 $42.00 $76.00 | 17 | |
Enhances Pronase activity by disrupting weak intramolecular interactions, potentially exposing more substrate binding sites. | ||||||
β-Mercaptoethanol | 60-24-2 | sc-202966A sc-202966 | 100 ml 250 ml | $88.00 $118.00 | 10 | |
Maintains a reducing environment crucial for Pronase activity, protecting sulfhydryl groups essential for its catalytic function. |