Date published: 2025-9-10

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Pronase激活剂

MAIR-II Activators are a diverse array of chemical compounds that, through their interaction with various biochemical pathways, serve to enhance the functionality of MAIR-II, a protein involved in immune cell regulation. Benzyl benzoate and Resolvin D1 play roles in modulating G protein-coupled receptor signaling, which could indirectly potentiate the activity of MAIR-II by influencing immune responses in which MAIR-II is involved. Anandamide, via the CB2 receptor, and PGE2, through its EP receptors, may augment the inhibitory signaling of MAIR-II, contributing to an anti-inflammatory state. Similarly, the action of Platelet-activating factor and Adenosine on their respective receptors can modulate immune cell pathways to amplify MAIR-II's regulatory effects. Lipoxin A4, by engaging with the ALX/FPR2 receptor, and NAD+, through its influence onMAIR-II Activators are chemical compounds that indirectly augment the functional activity of MAIR-II, a protein implicated in immune cell signaling.

Benzyl benzoate, which serves as a ligand for GPR50, may indirectly promote MAIR-II signaling by modulating GPR50 activity, potentially influencing immune cell responses that involve MAIR-II. Similarly, Resolvin D1 and Lipoxin A4, both acting on the ALX/FPR2 receptor, can enhance the anti-inflammatory signaling pathways where MAIR-II is active, contributing to the suppression of inflammation. Anandamide, which interacts with cannabinoid receptors, and PGE2, targeting EP receptors, are also capable of enhancing MAIR-II mediated actions in myeloid cells, reinforcing the protein's role in immune regulation. Platelet-activating factor and Adenosine, each acting through their specific receptors, can modulate immune responses in a manner that may potentiate MAIR-II's inhibitory effects, thereby dampening inflammation.

関連項目

Items 1 to 10 of 12 total

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产品名称CAS #产品编号数量价格应用排名

Sodium Chloride

7647-14-5sc-203274
sc-203274A
sc-203274B
sc-203274C
500 g
2 kg
5 kg
10 kg
$18.00
$23.00
$35.00
$65.00
15
(3)

通过优化离子强度增强 Pronase 的活性,这对保持其结构完整性和酶效率至关重要。

Calcium chloride anhydrous

10043-52-4sc-207392
sc-207392A
100 g
500 g
$65.00
$262.00
1
(1)

通过在特定位点结合稳定 Pronase 结构,促进有利于底物结合和催化的构象。

Magnesium sulfate anhydrous

7487-88-9sc-211764
sc-211764A
sc-211764B
sc-211764C
sc-211764D
500 g
1 kg
2.5 kg
5 kg
10 kg
$45.00
$68.00
$160.00
$240.00
$410.00
3
(1)

提供镁离子作为辅助因子,对 Pronase 的正常折叠和结构完整性至关重要。

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

为 Pronase 的结构稳定提供锌离子,帮助维持活性位点的几何形状,以有效发挥酶的作用。

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$56.00
$156.00
$270.00
$665.00
37
(1)

前列腺素 E2(PGE2)与免疫细胞上的 EP 受体相互作用,调节免疫反应。PGE2 信号可间接增加髓系细胞 MAIR-II 的抑制活性,从而抑制炎症反应。

Adenosine

58-61-7sc-291838
sc-291838A
sc-291838B
sc-291838C
sc-291838D
sc-291838E
sc-291838F
1 g
5 g
100 g
250 g
1 kg
5 kg
10 kg
$33.00
$47.00
$294.00
$561.00
$1020.00
$2550.00
$4590.00
1
(0)

腺苷与腺苷受体相互作用,后者参与抗炎反应。激活这些受体可能会促进有利于免疫抑制的信号通路,从而增强 MAIR-II 的活性。

Lipoxin A4

89663-86-5sc-201060
sc-201060A
sc-201060B
sc-201060C
25 µg
50 µg
100 µg
250 µg
$342.00
$485.00
$923.00
$2025.00
2
(1)

脂氧素A4是一种与ALX/FPR2受体结合的抗炎类花生酸。它可以通过促进MAIR-II参与的抗炎信号通路来增强MAIR-II的活性,从而有助于炎症的消退。

Glycerol

56-81-5sc-29095A
sc-29095
100 ml
1 L
$55.00
$150.00
12
(5)

作为一种稳定剂,通过影响水合外壳和微环境来增强 Pronase 的稳定性和活性。

Urea

57-13-6sc-29114
sc-29114A
sc-29114B
1 kg
2 kg
5 kg
$30.00
$42.00
$76.00
17
(1)

通过破坏微弱的分子内相互作用来增强 Pronase 的活性,从而可能暴露出更多的底物结合位点。

β-Mercaptoethanol

60-24-2sc-202966A
sc-202966
100 ml
250 ml
$88.00
$118.00
10
(2)

维持还原环境,对Pronase活性至关重要,保护硫氢基,对催化功能必不可少。