PRAME like-1 Activators
PRAME like-1 Activators represent a group of chemical compounds that directly enhance the functional activity of PRAME like-1, a protein that is directly involved in various cellular processes and signaling pathways. For instance, Forskolin, IBMX, and Rolipram are significant compounds that influence the cAMP-dependent pathway leading to the activation of Protein Kinase A (PKA), a pathway in which PRAME like-1 is directly involved. By increasing cAMP levels or inhibiting its degradation, these compounds can enhance the functional activity of PRAME like-1.
Moreover, PRAME like-1 activators also include neurotransmitters like Dopamine, Serotonin, Histamine, and Acetylcholine that act on specific receptor pathways. By activating these pathways, these neurotransmitters can enhance the function of PRAME like-1, which is involved in cellular processes downstream ofthese pathways. Furthermore, lipid compounds such as Prostaglandin E2 and Leukotriene B4 are also part of this category. They activate specific receptor pathways that PRAME like-1 is involved in, thereby directly enhancing its function. Lastly, Capsaicin, an activator of the TRPV1 ion channel, influences calcium-dependent signaling pathways that PRAME like-1 is a part of, leading to enhanced functional activity of this protein. In addition to these, Sphingosine 1-Phosphate and LPA have been identified as activators of the Rho GTPase signaling pathway, a pathway where PRAME like-1 is directly involved.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin directly activates adenylate cyclase which results in increased levels of cyclic AMP (cAMP). PRAME like-1, involved in the cAMP-dependent pathway leading to the activation of Protein Kinase A (PKA), sees enhanced function with increased cAMP levels due to Forskolin. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a non-selective inhibitor of phosphodiesterases (PDEs) leading to increased intracellular levels of cAMP. PRAME like-1, involved in the cAMP-dependent pathway leading to the activation of PKA, sees enhanced function with the inhibition of PDEs by IBMX. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram is a selective inhibitor of phosphodiesterase 4 (PDE4), leading to increased cAMP levels. PRAME like-1, involved in the cAMP-dependent pathway leading to the activation of PKA, sees enhanced function with the inhibition of PDE4 by Rolipram. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine 1-Phosphate activates the Rho GTPase signaling pathway. PRAME like-1, involved in cellular processes downstream of the Rho GTPase signaling pathway, sees enhanced function with the activation of this pathway by Sphingosine 1-Phosphate. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
LPA activates the Rho GTPase signaling pathway. PRAME like-1, involved in cellular processes downstream of the Rho GTPase signaling pathway, sees enhanced function with the activation of this pathway by LPA. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine is a neurotransmitter that activates the D1-D5 receptors pathway. PRAME like-1, involved in cellular processes downstream of this pathway, sees enhanced function with the activation of the dopaminergic pathway by Dopamine. | ||||||
Serotonin hydrochloride | 153-98-0 | sc-201146 sc-201146A | 100 mg 1 g | $118.00 $187.00 | 15 | |
Serotonin is a neurotransmitter that activates the 5-HT receptors pathway. PRAME like-1, involved in cellular processes downstream of this pathway, sees enhanced function with the activation of the serotonergic pathway by Serotonin. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine is a neurotransmitter that activates the H1-H4 receptors pathway. PRAME like-1, involved in cellular processes downstream of this pathway, sees enhanced function with the activation of the histaminergic pathway by Histamine. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 is a lipid compound that activates the prostaglandin E2 receptor EP1-EP4 pathway. PRAME like-1, involved in cellular processes downstream of this pathway, sees enhanced function with the activation of this pathway by Prostaglandin E2. | ||||||
LTB4 (Leukotriene B4) | 71160-24-2 | sc-201043 | 50 µg | $374.00 | 4 | |
Leukotriene B4 is a lipid compound that activates the LTB4 receptor BLT1/BLT2 pathway. PRAME like-1, involved in cellular processes downstream of this pathway, sees enhanced function with the activation of this pathway by Leukotriene B4. | ||||||