Date published: 2026-5-30

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POTE8 Inhibitors

POTE8 Inhibitors refer to a class of chemical compounds specifically designed to interact with and modulate the activity of the POTE8 protein. The POTE (Prostate, ovary, testis-expressed) family is a group of genes that code for a family of proteins primarily expressed in the prostate, ovary, and testis, although they have also been found in other tissues. POTE8, as a member of this family, is one of the several isoforms encoded by the POTE genes. While the precise functions of POTE8 are still under investigation, it is thought to be involved in various cellular processes, including cell growth, differentiation, or signaling pathways. Inhibitors of POTE8 are developed to engage with this specific protein and influence its interactions with other cellular components, its cellular localization, or its participation in the cellular processes where POTE8 is involved.

Structurally, POTE8 Inhibitors are designed to target specific binding sites or regions on the POTE8 protein. This interaction may disrupt the normal functioning of POTE8, affecting its ability to mediate protein-protein interactions or other molecular functions. Research focused on POTE8 Inhibitors contributes to our understanding of the roles of POTE8 and the broader POTE protein family in cellular physiology. Investigating the biochemical and functional aspects of POTE8 and its modulation by inhibitors can offer insights into the fundamental cellular processes where these proteins play a role, contributing to our knowledge of gene expression, cell biology, and their relevance in the context of reproductive tissues like the prostate, ovary, and testis. Additionally, exploring the functions of POTE8 may uncover its significance in various physiological and pathophysiological conditions beyond reproductive tissues.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$41.00
$84.00
$275.00
127
(6)

A known protein synthesis inhibitor. It binds to the 60S subunit of the eukaryotic ribosome, thus inhibiting translation.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Interferes with the action of RNA polymerase, leading to inhibition of RNA synthesis and, subsequently, protein synthesis.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

While known as an mTOR inhibitor, it can affect protein synthesis and function through the mTOR pathway.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

An inhibitor of phosphoinositide 3-kinases (PI3K), affecting various cellular processes including protein synthesis.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

A proteasome inhibitor that prevents protein degradation, affecting protein homeostasis in cells.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$99.00
$259.00
36
(2)

A protein synthesis inhibitor that acts on the 28S component of the ribosomal subunit.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$42.00
$214.00
$832.00
$66.00
394
(16)

Causes premature chain termination during translation, leading to the inhibition of protein synthesis.

Emetine

483-18-1sc-470668
sc-470668A
sc-470668B
sc-470668C
1 mg
10 mg
50 mg
100 mg
$440.00
$900.00
$1400.00
$2502.00
(0)

Inhibits protein synthesis by interfering with the action of elongation factor 2.

Mitoxantrone

65271-80-9sc-207888
100 mg
$285.00
8
(1)

An anti-cancer drug that intercalates into DNA, disrupting DNA synthesis and function, which can affect protein expression.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$176.00
$426.00
43
(3)

Intercalates into DNA, causing DNA damage and affecting RNA and protein synthesis.