Date published: 2025-10-19

1-800-457-3801

SCBT Portrait Logo
Seach Input

Potassium Channel Modulators

Santa Cruz Biotechnology now offers a broad range of potassium channel modulators for use in various applications. Potassium channel modulators are critical tools in neuroscience and physiology research, as they regulate the function of potassium channels, which are integral to maintaining the membrane potential and regulating cellular excitability. These modulators include both activators and inhibitors, allowing researchers to precisely control potassium channel activity and study its effects on cellular processes. Potassium channels are involved in various physiological functions, including cardiac rhythm, muscle contraction, and neuronal signaling. Researchers utilize potassium channel modulators to investigate the role of these channels in normal cellular function and their involvement in diseases such as epilepsy, arrhythmias, and hypertension. By manipulating potassium channel activity, scientists can elucidate the underlying mechanisms of channelopathies and explore new fundemental targets. These modulators are also used in drug discovery and development, as they provide insights into the pharmacological properties and potential side effects of new compounds. By offering a comprehensive selection of high-quality potassium channel modulators, Santa Cruz Biotechnology supports advanced research in biochemistry and molecular biology. These products enable precise and reproducible experiments, driving innovations in our understanding of ion channel physiology and the development of novel scientific strategies. View detailed information on our available potassium channel modulators by clicking on the product name.

Items 31 to 40 of 103 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AM 92016 hydrochloride

178894-81-0sc-203506
sc-203506A
10 mg
50 mg
$230.00
$1148.00
(0)

AM 92016 hydrochloride functions as a potassium channel modulator by engaging with distinct allosteric sites on the channel protein, inducing structural rearrangements that modify ion flow. Its unique chemical architecture promotes specific interactions with surrounding lipid bilayers, enhancing membrane fluidity. This compound also exhibits differential kinetics in ion conductance, impacting the overall ionic balance and influencing cellular homeostasis and signaling pathways.

Aprindine hydrochloride

33237-74-0sc-252383
10 mg
$125.00
(0)

Aprindine hydrochloride acts as a potassium channel modulator by selectively binding to specific sites on the channel, leading to conformational changes that alter ion permeability. Its unique structure facilitates interactions with membrane components, potentially affecting channel gating dynamics. The compound demonstrates varied reaction kinetics, influencing the rate of ion transport and contributing to the modulation of electrical activity across cellular membranes.

L-364,373

103342-82-1sc-204036
sc-204036B
sc-204036C
2.5 mg
5 mg
10 mg
$240.00
$469.00
$877.00
(1)

L-364,373 functions as a potassium channel modulator by engaging with distinct allosteric sites, inducing specific conformational shifts that enhance or inhibit channel activity. Its unique molecular architecture allows for selective interactions with lipid bilayers, influencing membrane fluidity and channel accessibility. The compound exhibits unique kinetic profiles, affecting the timing and magnitude of ion flux, thereby playing a critical role in cellular excitability and signaling pathways.

CP 339818 hydrochloride

185855-91-8sc-203903
sc-203903A
10 mg
50 mg
$155.00
$660.00
(0)

CP 339818 hydrochloride acts as a potassium channel modulator by selectively binding to specific sites on the channel protein, leading to alterations in ion conductance. Its unique structural features facilitate interactions with surrounding lipid environments, potentially stabilizing channel conformations. The compound demonstrates distinct reaction kinetics, influencing the rate of ion transport and contributing to the modulation of electrical signaling in various cellular contexts.

UCL 1684 ditrifluoroacetate

201147-19-5sc-253818
5 mg
$281.00
1
(1)

UCL 1684 ditrifluoroacetate functions as a potassium channel modulator through its ability to interact with the channel's gating mechanisms. Its unique trifluoroacetate groups enhance hydrophobic interactions, promoting conformational changes in the channel protein. This compound exhibits specific binding affinities that influence ion selectivity and permeability, thereby affecting the overall electrochemical gradients across membranes. Its kinetic profile reveals a nuanced impact on channel activation and inactivation dynamics.

Paxillinol

sc-205792
2 mg
$153.00
(0)

Paxillinol acts as a potassium channel modulator by selectively binding to specific sites on the channel protein, altering its conformational state. This compound's unique structural features facilitate enhanced interactions with lipid bilayers, influencing channel stability and function. Its modulation of ion flow is characterized by distinct reaction kinetics, which can lead to variations in channel responsiveness under different physiological conditions. The compound's ability to fine-tune ion conductance plays a crucial role in cellular excitability.

Tertiapin LQ

sc-362807
1 mg
$175.00
(0)

Tertiapin LQ functions as a potassium channel modulator through its specific binding to the channel's pore region, leading to a unique alteration in ion selectivity. Its distinct molecular structure allows for enhanced affinity towards certain channel subtypes, influencing gating mechanisms. The compound exhibits unique reaction kinetics, resulting in prolonged channel inhibition, which can significantly affect cellular signaling pathways and excitability. Its interactions with membrane components further modulate channel dynamics.

Rutaecarpine

84-26-4sc-205846
sc-205846A
10 mg
25 mg
$123.00
$359.00
1
(0)

Rutaecarpine acts as a potassium channel modulator by selectively interacting with the channel's voltage-sensing domains, which alters the conformational state of the channel. This compound exhibits a unique ability to stabilize specific channel states, influencing the kinetics of ion flow. Its distinct molecular interactions can lead to differential modulation of various potassium channel subtypes, thereby impacting cellular excitability and signaling cascades in a nuanced manner.

Doxapram

309-29-5sc-279007
5 mg
$100.00
(0)

Doxapram functions as a potassium channel modulator by engaging with the channel's pore region, facilitating alterations in ion permeability. Its unique binding dynamics can enhance or inhibit channel activity, depending on the specific subtype involved. This compound exhibits a rapid onset of action, with reaction kinetics that allow for swift modulation of membrane potential. Additionally, its interactions can influence downstream signaling pathways, contributing to a complex regulatory network within cellular environments.

Adenosine 5′-Triphosphate, disodium salt

987-65-5sc-202040
sc-202040A
1 g
5 g
$38.00
$74.00
9
(1)

Adenosine 5'-Triphosphate, disodium salt acts as a potassium channel modulator by interacting with specific binding sites on the channel, leading to conformational changes that affect ion flow. Its unique structure allows for differential modulation of various potassium channel subtypes, influencing their gating mechanisms. The compound's rapid hydrolysis in cellular environments results in dynamic shifts in energy states, impacting cellular excitability and signaling cascades.