CP 339818 hydrochloride CAS: 185855-91-8
MF: C21H24N2•HCl
MW: 340.89
A non-peptide and inhibitor of Kv1.3.

CP 339818 hydrochloride (CAS 185855-91-8)

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Alternate Names: N-[1-(Phenylmethyl)-4(1H)-quinolinylidene]-1 pentanamine hydrochloride
Application: CP 339818 hydrochloride is a non-peptide and inhibitor of Kv1.3
CAS Number: 185855-91-8
Purity: ≥99%
Molecular Weight: 340.89
Molecular Formula: C21H24N2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

CP 339818 hydrochloride is a non-peptide. It inhibits Kv1.3 in a use-dependent manner by preferentially blocking the C-type inactivated state of the channel. It appears to recognize only the inactivated conformation of Kv1.3. CP 339818 hydrochloride is an inhibitor of KV1.4.


References

1. Nguyen, A., et al. 1996. Mol. Pharmacol. 50: 1672-1679. PMID: 8967992
2. Jäger, H., et al. 1998. J. Physiol. 506: 291-301. PMID: 9490854

Physical State :
Solid
Solubility :
Soluble in water (20 mM).
Storage :
Store at room temperature
Boiling Point :
450.5° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
IC50 :
KV1.3: IC50 = ~200 nM; KV1.4: IC50 = ~300 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
20761468
MDL Number :
MFCD09878238
SMILES :
CCCCCN=C1C=CN(C2=CC=CC=C12)CC3=CC=CC=C3.Cl

Download SDS (MSDS)

Certificate of Analysis

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