PORCN Activators represent a group of chemicals that can potentially influence PORCN activity indirectly through their impacts on the Wnt signaling pathway. This group includes diverse molecules such as Lithium Chloride, Epinephrine, Quercetin, Resveratrol, Curcumin, Genistein, Indole-3-carbinol, Sulforaphane, Retinoic Acid, Ascorbic Acid, Nicotinamide, and Folic Acid.
These compounds are known to influence various signaling pathways and cellular processes. For example, Lithium Chloride can inhibit GSK-3β, thereby stabilizing β-catenin and promoting Wnt signaling. This could potentially influence PORCN activity indirectly, as this protein is involved in the palmitoylation of Wnt proteins. Similarly, other compounds like Epinephrine, Quercetin, Resveratrol, Curcumin, Genistein, Indole-3-carbinol, Sulforaphane, Retinoic Acid, Ascorbic Acid, Nicotinamide, and Folic Acid can influence different aspects of cellular signaling, potentially affecting the Wnt signaling pathway and thereby indirectly influencing PORCN activity. Thus, while not direct activators of PORCN, these compounds could potentially influence its activity indirectly through their effects on the Wnt signaling pathway and other related cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride can inhibit GSK-3β, thereby stabilizing β-catenin and promoting Wnt signaling, potentially influencing PORCN activity indirectly. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine may influence various cellular processes, potentially impacting Wnt signaling and thus indirectly affecting PORCN activity. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has been shown to influence Wnt/β-catenin signaling, potentially affecting PORCN activity indirectly. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can impact various signaling pathways, including Wnt signaling, potentially affecting PORCN activity indirectly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin may influence various signaling pathways, including Wnt signaling, potentially affecting PORCN activity indirectly. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein can influence various signaling pathways, including Wnt signaling, potentially affecting PORCN activity indirectly. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Indole-3-carbinol may influence various signaling pathways, including Wnt signaling, potentially affecting PORCN activity indirectly. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane can impact various signaling pathways, including Wnt signaling, potentially affecting PORCN activity indirectly. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid can influence various signaling pathways, including Wnt signaling, potentially affecting PORCN activity indirectly. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Ascorbic Acid may influence various cellular processes, potentially impacting Wnt signaling and thus indirectly affecting PORCN activity. | ||||||