Date published: 2026-4-26

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POMC Antibodies

Santa Cruz Biotechnology features a diverse variety of POMC monoclonal antibodies for various research applications. POMC Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Pro-opiomelanocortin (POMC) is a precursor polypeptide that plays a crucial role in the regulation of several physiological processes, including stress response, energy homeostasis, and pigmentation. POMC is cleaved into several active peptides, including adrenocorticotropic hormone (ACTH) and melanocyte-stimulating hormones (MSH), which are essential for the body's response to stress and the regulation of appetite. Understanding the function of POMC and its derivatives is vital for research into metabolic disorders and stress-related conditions. POMC monoclonal antibodies enable precise detection and analysis of POMC expression patterns across different tissues and experimental conditions. Researchers can investigate POMC's role in various biological pathways and cellular mechanisms. POMC monoclonal antibodies from Santa Cruz Biotechnology support scientists worldwide in advancing our understanding of metabolic regulation and stress response mechanisms.

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POMC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

β-endorphin Antibody (B31.15)

sc-51680mouse IgG1(h)IF, IHC(P)h
2
(1)

β-endorphin Antibody (2Q2194)

sc-71044mouse IgG1(h)IF, IHC(P)h

new

(1)

Met/Leu-enkephalin Antibody (NOC1/35)

sc-47705mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
10
(4)

POMC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

POMC CRISPR/Cas9 KO Plasmid (h)

sc-400592hGene KnockoutGFP0
(0)

POMC CRISPR/Cas9 KO Plasmid (m)

sc-422342mGene KnockoutGFP0
(0)

POMC HDR Plasmid (m)

sc-422342-HDRmHomology Directed RepairPuromycin0
(0)

POMC CRISPR/Cas9 KO Plasmid (r)

sc-437377rGene KnockoutGFP0
(0)

POMC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

POMC CRISPR Activation Plasmid (h)

sc-400592-ACThGene ActivationPuro, Blast, Hygro0
(0)

POMC CRISPR Activation Plasmid (h2)

sc-400592-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

POMC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

POMC siRNA (h)

sc-37277hGene SilencingN/A
1
(0)

POMC shRNA Plasmid (h)

sc-37277-SHhGene SilencingPuromycin
1
(0)

POMC shRNA (h) Lentiviral Particles

sc-37277-VhGene SilencingPuromycin
1
(0)

POMC siRNA (m)

sc-37278mGene SilencingN/A
1
(0)

POMC shRNA Plasmid (m)

sc-37278-SHmGene SilencingPuromycin
1
(0)

POMC shRNA (m) Lentiviral Particles

sc-37278-VmGene SilencingPuromycin
1
(0)