β-endorphin Antibody (2Q2194): sc-71044

β-endorphin Antibody (2Q2194) is a mouse monoclonal IgG1 antibody specifically designed to detect β-endorphin, a 31-amino-acid peptide derived from the precursor protein pro-opiomelanocortin (POMC). β-endorphin monoclonal antibody (2Q2194) reacts with human β-endorphin in immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP), making this tool valuable for studying the expression and localization of this peptide. β-endorphin, also known as beta-endorphin, is an endogenous opioid neuropeptide that plays a crucial role in pain modulation, stress response, and immune system regulation. Produced primarily in neurons of the hypothalamus and the pituitary gland, β-endorphin binds to opioid receptors to exert analgesic and euphoric effects, which are important for the body′s natural pain control and stress relief mechanisms. β-endorphin is generated through the cleavage of POMC, a 267-amino-acid polypeptide that undergoes extensive tissue-specific post-translational processing. Mutations in the POMC gene can lead to POMC deficiency, characterized by red hair, adrenal insufficiency, and susceptibility to obesity. Understanding the function of β-endorphin is essential for research into pain management, addiction, mood disorders, and metabolic diseases. β-endorphin (2Q2194) antibody provides researchers with a reliable means to detect and study this important peptide, facilitating advances in neuroscience and endocrinology.

The preferred ACTH antibody is ACTH Antibody (2F6): sc-69648.