PLSCR2 Inhibitors
PLSCR2 inhibitors are a class of chemical compounds that target and modulate the activity of Phospholipid Scramblase 2 (PLSCR2), a protein primarily found in the plasma membrane of various cell types. PLSCR2 is a member of the phospholipid scramblase family, which plays a critical role in mediating the bidirectional translocation of phospholipids between the inner and outer leaflets of the cell membrane. This translocation of phospholipids is essential for maintaining the integrity and asymmetry of the cell membrane, which is crucial for various cellular processes, including membrane fusion, vesicle trafficking, and cell signaling.
PLSCR2 inhibitors are designed to specifically interact with PLSCR2 and modulate its activity, inhibiting its phospholipid scrambling function or interfering with its interactions with other cellular components. By doing so, these inhibitors can impact various cellular processes that rely on the dynamic redistribution of phospholipids in the cell membrane. Understanding the mechanisms of action and specificity of PLSCR2 inhibitors is critical for elucidating their roles in cellular biology and uncovering novel insights into the regulation of cell membrane dynamics. Further research is needed to fully characterize the biochemical and cellular effects of PLSCR2 inhibitors and their applications in various research contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Gill′s Hematoxylin Solution, No. 2 | 517-28-2 | sc-24973 sc-24973A | 100 ml 1 L | $25.00 $150.00 | 76 | |
Hematoxylin is a natural compound that inhibits PLSCR2 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol modulates PLSCR2 through its anti-inflammatory properties. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein may inhibit PLSCR2 activation by interfering with signaling pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin exhibits anti-PLSCR2 activity via its anti-inflammatory effects. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin may downregulate PLSCR2 expression in certain cellular contexts. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is known for its anti-inflammatory effects, possibly affecting PLSCR2. | ||||||
Rutin trihydrate | 250249-75-3 | sc-204897 sc-204897A sc-204897B | 5 g 50 g 100 g | $56.00 $71.00 $124.00 | 7 | |
Rutin can modulate PLSCR2 activity through its anti-oxidative properties. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $31.00 $41.00 $159.00 $286.00 | 12 | |
Baicalein may interfere with PLSCR2 function via anti-inflammatory actions. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is believed to influence PLSCR2 via anti-inflammatory and antioxidant effects. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
Aspirin might indirectly affect PLSCR2 by inhibiting inflammatory pathways. | ||||||