Date published: 2026-3-3

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Rutin trihydrate (CAS 250249-75-3)

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Alternate Names:
Vitamin P trihydrate; Quercetin-3-rutinoside trihydrate
Application:
Rutin trihydrate is an antioxidant flavonoid and Nitric Oxide scavenger
CAS Number:
250249-75-3
Purity:
≥95%
Molecular Weight:
664.56
Molecular Formula:
C27H30O163H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Rutin trihydrate is an antioxidant flavonoid and Nitric oxide (NO) scavenger.Rutin trihydrate, a flavonoid glycoside present in numerous plants. Functioning as a polyphenol, this compound exhibits a diverse array of biological activities, including valuable anti-inflammatory, antioxidant, and antifungal properties. In scientific investigations, rutin trihydrate has been extensively explored, revealing its ability to effectively combat inflammation by inhibiting the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha and interleukin-6.


Rutin trihydrate (CAS 250249-75-3) References

  1. Antioxidant activity of citrus limonoids, flavonoids, and coumarins.  |  Yu, J., et al. 2005. J Agric Food Chem. 53: 2009-14. PMID: 15769128
  2. Characterization and evaluation of a macroporous adsorbent for possible use in the expanded bed adsorption of flavonoids from Ginkgo biloba L.  |  Li, J. and Chase, HA. 2009. J Chromatogr A. 1216: 8730-40. PMID: 19304292
  3. In vitro antioxidant and radical scavenging of Guinean kinkeliba leaf (Combretum micranthum G. Don) extracts.  |  Touré, A., et al. 2011. Nat Prod Res. 25: 1025-36. PMID: 21480049
  4. Analysis of flavonoids by graphene-based surface-assisted laser desorption/ionization time-of-flight mass spectrometry.  |  Liu, CW., et al. 2012. Analyst. 137: 5809-16. PMID: 23096162
  5. Flavonoids and 5-aminosalicylic acid inhibit the formation of neutrophil extracellular traps.  |  Kirchner, T., et al. 2013. Mediators Inflamm. 2013: 710239. PMID: 24381411
  6. Effects of rutin and buckwheat seeds on energy metabolism and methane production in dairy cows.  |  Stoldt, AK., et al. 2016. J Dairy Sci. 99: 2161-2168. PMID: 26805964
  7. Injectable dynamic covalent hydrogels of boronic acid polymers cross-linked by bioactive plant-derived polyphenols.  |  Huang, Z., et al. 2018. Biomater Sci. 6: 2487-2495. PMID: 30069570
  8. An evaluation of bioactive compounds, fatty acid composition and oil quality of chia (Salvia hispanica L.) seed roasted at different temperatures.  |  Ghafoor, K., et al. 2020. Food Chem. 333: 127531. PMID: 32679420
  9. Protective Effect of Rutin Trihydrate Against Dose-Dependent, Cisplatin-Induced Cardiac Toxicity in Isolated Perfused Rat's Heart.  |  Bukhari, IA., et al. 2022. Cureus. 14: e21572. PMID: 35228931
  10. Protective Effect of Organ Preservation Fluid Supplemented With Nicorandil and Rutin Trihydrate: A Comparative Study in a Rat Model of Renal Ischemia.  |  Sharma, N., et al. 2022. Exp Clin Transplant. 20: 569-579. PMID: 35791830
  11. Evaluation of potential inhibitory effects on acetylcholinesterase, pancreatic lipase, and cancer cell lines using raw leaves extracts of three fabaceae species.  |  Fatima, I., et al. 2023. Heliyon. 9: e15909. PMID: 37206037
  12. Screening for agents inhibiting the mutagenicity of extracts and constituents of tobacco products.  |  Romert, L., et al. 1994. Mutat Res. 322: 97-110. PMID: 7519327

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Rutin trihydrate, 5 g

sc-204897
5 g
$57.00

Rutin trihydrate, 50 g

sc-204897A
50 g
$72.00

Rutin trihydrate, 100 g

sc-204897B
100 g
$126.00