Date published: 2026-5-16

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PIG-F Activators

The PIG-F gene encodes a critical enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors, which are essential for anchoring proteins to the cell membrane. PIG-F plays a key role in catalyzing the addition of ethanolamine phosphate to the third mannose of the GPI anchor precursor, facilitating its attachment to proteins. Functionally, PIG-F is vital for the proper localization and function of GPI-anchored proteins, which are involved in various cellular processes, including cell signaling, adhesion, and immune response. Activation of PIG-F is orchestrated by a series of biochemical events that regulate the biosynthesis of GPI anchors. Several key nutrients and cofactors, such as folic acid, inositol, and choline, play crucial roles in promoting PIG-F activation by ensuring the availability of substrates and cofactors required for GPI anchor biosynthesis. Additionally, trace elements like zinc, selenium, and iron serve as cofactors for enzymes involved in GPI anchor synthesis, indirectly supporting PIG-F activity by facilitating enzymatic reactions. Overall, the coordinated action of these chemicals and cofactors ensures the efficient assembly and activation of GPI-anchored proteins, including PIG-F, thereby contributing to cellular membrane integrity and function.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Activates PIG-F by enhancing the expression of enzymes involved in the glycosylphosphatidylinositol (GPI) anchor biosynthesis pathway, thus promoting GPI anchor formation and PIG-F activation.

Folic Acid

59-30-3sc-204758
10 g
$73.00
2
(1)

Functions as a cofactor in the biosynthesis of GPI anchors, indirectly activating PIG-F by ensuring the availability of substrates required for the synthesis of GPI anchors.

Ethanolamine

141-43-5sc-203042
sc-203042A
sc-203042B
25 ml
500 ml
2.5 L
$22.00
$56.00
$204.00
1
(1)

Indirectly activates PIG-F by providing a substrate for the synthesis of ethanolamine phosphate, a component of GPI anchors, thereby facilitating the assembly and activation of PIG-F.

Inositol

6917-35-7sc-394417
100 g
$79.00
(0)

Stimulates the biosynthesis of GPI anchors, leading to increased availability of GPI-anchored proteins, including PIG-F, at the cell surface, thereby promoting PIG-F activation.

Choline chloride

67-48-1sc-207430
sc-207430A
sc-207430B
10 mg
5 g
50 g
$33.00
$37.00
$52.00
1
(1)

Promotes the synthesis of phosphatidylcholine, a precursor of GPI anchors, indirectly activating PIG-F by contributing to the availability of lipid moieties required for GPI anchor biosynthesis.

L-Serine

56-45-1sc-397670
sc-397670A
sc-397670B
sc-397670C
sc-397670D
1 g
100 g
1 kg
5 kg
10 kg
$20.00
$133.00
$546.00
$1224.00
$2040.00
(0)

Enhances the synthesis of serine-derived lipids, such as phosphatidylserine, which are important components of GPI anchors, indirectly activating PIG-F by facilitating the biosynthesis of GPI anchors.

D(+)Glucose, Anhydrous

50-99-7sc-211203
sc-211203B
sc-211203A
250 g
5 kg
1 kg
$38.00
$198.00
$65.00
5
(1)

Acts as a substrate for the synthesis of mannose, a component of GPI anchors, indirectly activating PIG-F by providing the necessary building blocks for GPI anchor biosynthesis.

D-Mannose

3458-28-4sc-211180
sc-211180A
100 g
250 g
$103.00
$161.00
1
(1)

Stimulates the biosynthesis of GPI anchors by serving as a substrate for the attachment of the glycan moiety, thereby promoting the assembly and activation of GPI-anchored proteins, including PIG-F.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

Functions as a cofactor for enzymes involved in GPI anchor biosynthesis, indirectly activating PIG-F by facilitating the enzymatic reactions necessary for GPI anchor formation.

Selenium

7782-49-2sc-250973
50 g
$62.00
1
(1)

Acts as a cofactor for selenoproteins involved in various cellular processes, including GPI anchor biosynthesis, indirectly promoting PIG-F activation by supporting the activity of selenoprotein-dependent enzymes required for GPI anchor synthesis.