PI 3-kinase p110 alpha Inhibitors
Items 11 to 20 of 25 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
DNA-PK Inhibitor IV | sc-221562 sc-221562A sc-221562B | 1 mg 100 mg 20 mg | $30.00 $200.00 $50.00 | |||
DNA-PK Inhibitor IV is a potent inhibitor targeting the PI 3-kinase p110 alpha isoform, distinguished by its ability to selectively disrupt the enzyme's active site interactions. This compound exhibits a unique mechanism of action, modulating the phosphorylation of key substrates and influencing cellular signaling pathways. Its reaction kinetics suggest a competitive inhibition model, providing insights into the regulatory roles of PI 3-kinase in various biological contexts. | ||||||
PI 3-Kα Inhibitor IV | sc-222170 | 5 mg | $223.00 | 2 | ||
PI 3-Kα Inhibitor IV is a selective inhibitor of the PI 3-kinase p110 alpha isoform, characterized by its ability to engage in specific hydrogen bonding and hydrophobic interactions within the enzyme's active site. This compound alters the conformational dynamics of the kinase, impacting downstream signaling cascades. Its kinetic profile indicates a non-competitive inhibition mechanism, revealing insights into the intricate regulatory networks governed by PI 3-kinase activity. | ||||||
DNA-PK Inhibitor III | 404009-40-1 | sc-203928 | 1 mg | $194.00 | ||
DNA-PK Inhibitor III selectively targets the PI 3-kinase p110 alpha isoform, exhibiting a unique binding affinity that stabilizes the enzyme's inactive conformation. This compound disrupts the phosphorylation process by modulating the enzyme's allosteric sites, leading to altered substrate accessibility. Its reaction kinetics suggest a mixed inhibition pattern, providing a nuanced understanding of the regulatory mechanisms that influence cellular signaling pathways. | ||||||
AS-604850 | 648449-76-7 | sc-221271 sc-221271A | 1 mg 5 mg | $36.00 $130.00 | ||
AS-604850 is a selective inhibitor of the PI 3-kinase p110 alpha isoform, characterized by its ability to engage in specific hydrogen bonding interactions with key residues in the enzyme's active site. This compound alters the enzyme's conformational dynamics, effectively hindering its catalytic activity. Its kinetic profile indicates competitive inhibition, revealing insights into the intricate balance of lipid signaling pathways and their regulatory networks within cellular environments. | ||||||
PI 3-Kγ Inhibitor | 648450-29-7 | sc-203191 | 5 mg | $76.00 | ||
PI 3-Kγ Inhibitor is a targeted modulator of the PI 3-kinase p110 gamma isoform, distinguished by its unique ability to disrupt protein-protein interactions crucial for signal transduction. This compound exhibits allosteric inhibition, leading to a conformational shift that impairs substrate binding. Its reaction kinetics suggest a non-competitive mechanism, providing a nuanced understanding of lipid metabolism and cellular signaling cascades, influencing various downstream effects. | ||||||
AS-605240 | 648450-29-7 | sc-221272 sc-221272A | 1 mg 5 mg | $23.00 $80.00 | 1 | |
AS-605240 is a selective inhibitor of the PI 3-kinase p110 alpha isoform, characterized by its capacity to interfere with lipid kinase activity. This compound engages in specific molecular interactions that alter the enzyme's active site, resulting in a reduction of phosphoinositide production. Its kinetic profile indicates a reversible binding mechanism, allowing for fine-tuning of cellular signaling pathways and metabolic processes, thereby impacting various cellular responses. | ||||||
AS-252424 | 900515-16-4 | sc-202961 sc-202961A | 1 mg 5 mg | $42.00 $158.00 | ||
AS-252424 is a potent inhibitor targeting the PI 3-kinase p110 alpha isoform, distinguished by its ability to modulate lipid signaling pathways. This compound exhibits unique binding dynamics, engaging in allosteric interactions that stabilize the inactive conformation of the enzyme. Its reaction kinetics reveal a competitive inhibition pattern, effectively disrupting the phosphorylation of key substrates. This modulation influences downstream signaling cascades, affecting cellular growth and survival mechanisms. | ||||||
LY 294002, 4′-NH2 | 942289-87-4 | sc-203121 sc-203121A | 5 mg 50 mg | $357.00 $2040.00 | 1 | |
LY 294002, 4′-NH2 is a selective inhibitor of the PI 3-kinase p110 alpha isoform, characterized by its ability to disrupt lipid metabolism. It interacts with the enzyme's active site, leading to a conformational shift that impedes substrate access. The compound demonstrates a unique kinetic profile, exhibiting non-competitive inhibition that alters the phosphorylation dynamics of critical signaling molecules. This interference can significantly impact cellular processes, including metabolism and apoptosis. | ||||||
AS 041164 | 1146702-72-8 | sc-291912 sc-291912A | 1 mg 5 mg | $23.00 $65.00 | ||
AS 041164 is a selective inhibitor targeting the PI 3-kinase p110 alpha isoform, known for its unique ability to modulate intracellular signaling pathways. It binds to the enzyme's regulatory domain, inducing a structural alteration that affects its catalytic activity. This compound exhibits a distinct kinetic behavior, functioning as a mixed inhibitor, which influences the phosphorylation of downstream effectors. Its interactions can lead to altered cellular responses, impacting growth and survival mechanisms. | ||||||
2-Bromobenzenesulfonyl chloride | 2905-25-1 | sc-254178 sc-254178A | 1 g 5 g | $27.00 $67.00 | ||
2-Bromobenzenesulfonyl chloride acts as a potent electrophile, engaging in nucleophilic substitution reactions due to its reactive sulfonyl chloride group. This compound selectively modifies amino acid residues in proteins, particularly targeting cysteine and serine residues, which can lead to significant changes in protein conformation and function. Its reactivity profile allows for rapid and specific covalent bonding, facilitating the exploration of protein interactions and signaling pathways. | ||||||