Molecular structure of DNA-PK Inhibitor IV
DNA-PK Inhibitor IV
Alternate Names:
2-Hydroxy-4-morpholin-4-yl-benzaldehyde
Application:
DNA-PK Inhibitor IV is a potent, selective, ATP-competitive DNA-PK inhibitor
Molecular Weight:
207.23
Molecular Formula:
C11H13NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A morpholino-salicylaldehyde compound which acts as a potent, selective and ATP-competitive inhibitor of DNA-PK. Inhibits PI 3-K catalytic subunit p110-isozymes at higher concentrations and weakly inhibits a panel of several other kinases.
DNA-PK Inhibitor IV References
- DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer. | Kashishian, A., et al. 2003. Mol Cancer Ther. 2: 1257-64. PMID: 14707266
- A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. | Willmore, E., et al. 2004. Blood. 103: 4659-65. PMID: 15010369
- Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold. | Knight, ZA., et al. 2004. Bioorg Med Chem. 12: 4749-59. PMID: 15358300
- Molecular mechanisms of anti-proliferative effects of the Traditional Chinese Medicinal compound Rocaglamide A on cancers[D]., | Neumann J. 2012.
Inhibitor of:
DNA-PK, PI 3-kinase p110 alpha, PI 3-kinase p110 beta, and PI 3-kinase p110 delta.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DNA-PK Inhibitor IV, 1 mg | sc-221562 | 1 mg | $30.00 | |||
DNA-PK Inhibitor IV, 20 mg | sc-221562B | 20 mg | $50.00 | |||
DNA-PK Inhibitor IV, 100 mg | sc-221562A | 100 mg | $200.00 |