Date published: 2026-4-24

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PHF21A Activators

PHF21A Activators belong to a distinct chemical class known for their ability to modulate the activity of the PHF21A gene. PHF21A, or PHD finger protein 21A, is a member of the PHD finger protein family, which plays a crucial role in epigenetic regulation. The PHD finger is a conserved motif found in many chromatin-associated proteins, and it is involved in recognizing and binding to specific histone modifications. PHF21A, in particular, has been identified as an important factor in chromatin organization and transcriptional regulation.

The activators associated with PHF21A function by influencing the gene's activity, potentially enhancing its role in epigenetic processes. These small molecules or compounds are designed to interact with the PHF21A protein, affecting its binding affinity to histones or other chromatin components. This modulation of PHF21A activity can lead to downstream effects on gene expression patterns and cellular processes. The discovery and development of PHF21A activators represent a significant advancement in the field of epigenetics, shedding light on the intricate mechanisms underlying chromatin dynamics. Further research into the precise molecular interactions and downstream effects of these activators may unveil new insights into the fundamental processes governing gene regulation and could have implications in various biological contexts.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is a powerful antioxidant that can indirectly activate PHF21A by reducing oxidative stress, which is a known regulator of PHF21A activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol can indirectly activate PHF21A by modulating the sirtuin pathway, which impacts histone modification processes that PHF21A is involved in.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin may indirectly activate PHF21A through its effect on NF-κB signaling, a pathway known to influence PHF21A.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin can indirectly activate PHF21A through AMPK activation, a pathway that may influence PHF21A activity.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate can indirectly activate PHF21A through histone deacetylase inhibition, which impacts histone modification processes PHF21A is involved in.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin indirectly activates PHF21A by increasing intracellular cAMP levels, thereby influencing pathways that interact with PHF21A.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D3 can indirectly activate PHF21A through the regulation of calcium signaling, a pathway that may influence PHF21A.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride can indirectly activate PHF21A by inhibiting GSK3β, a kinase that may influence PHF21A activity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin can indirectly activate PHF21A through its effects on the PI3K/Akt pathway, a known regulator of PHF21A.

Trolox

53188-07-1sc-200810
sc-200810A
sc-200810B
sc-200810C
sc-200810D
500 mg
1 g
5 g
25 g
100 g
$38.00
$67.00
$235.00
$678.00
$1712.00
39
(1)

Trolox, a water-soluble analogue of vitamin E, can indirectly activate PHF21A by reducing oxidative stress, which is a known regulator of PHF21A activity.