Date published: 2026-5-22

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Peg10 Inhibitors

Peg10 Inhibitors refer to a diverse class of chemical compounds designed to target and modulate the activity of the PEG10 gene, primarily by interfering with its expression or function. PEG10, which stands for Paternally Expressed Gene 10, is a unique imprinted gene in mammals, implicated in various cellular processes, including cell proliferation, apoptosis, and cancer development. Inhibitors within this class act as valuable tools for researchers and scientists to investigate the intricate mechanisms through which PEG10 influences these processes. These compounds exhibit diverse chemical structures and mechanisms of action, enabling a comprehensive exploration of PEG10's roles in cellular biology.

The mechanisms by which Peg10 Inhibitors function can vary widely. Some compounds focus on epigenetic regulation, impacting PEG10 gene expression by targeting DNA methylation or histone modifications within its regulatory regions. Others may affect post-transcriptional processing, mRNA stability, or translation of PEG10 transcripts. Additionally, Peg10 Inhibitors can potentially interfere with the interactions between PEG10 and its downstream targets, inhibiting specific cellular pathways or signaling cascades associated with PEG10 function. By providing a suite of chemical tools to manipulate PEG10, this class of inhibitors empowers researchers to unravel the complex web of molecular events associated with PEG10's role in normal cellular physiology and disease states. Understanding the mechanisms and consequences of PEG10 inhibition can pave the way for new insights into the fundamental biology of this gene and its potential implications in various biological contexts.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Zebularine

3690-10-6sc-203315
sc-203315A
sc-203315B
10 mg
25 mg
100 mg
$129.00
$284.00
$1004.00
3
(1)

Zebularine is a DNA methyltransferase inhibitor that prevents the methylation of PEG10 promoter region, leading to reduced PEG10 gene expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

This inhibitor, also known as Decitabine, works similarly to Zebularine by inhibiting DNA methyltransferases and demethylating the PEG10 promoter.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$131.00
$515.00
2
(1)

RG108 is a small molecule inhibitor of DNA methyltransferases, including those involved in PEG10 promoter methylation.

Scriptaid

287383-59-9sc-202807
sc-202807A
1 mg
5 mg
$64.00
$183.00
11
(2)

Scriptaid is a histone deacetylase (HDAC) inhibitor that modulates epigenetic regulation, indirectly affecting PEG10 expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This cytidine analog incorporates into DNA and inhibits DNA methyltransferases, impacting PEG10 promoter methylation.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic acid is an HDAC inhibitor that can influence PEG10 expression by altering histone acetylation patterns.

UNC0638

1255580-76-7sc-397012
10 mg
$315.00
(0)

UNC0638 is a G9a histone methyltransferase inhibitor, indirectly influencing PEG10 expression through histone methylation changes.

EPZ6438

1403254-99-8sc-507456
1 mg
$66.00
(0)

EPZ-6438 is an EZH2 histone methyltransferase inhibitor that modulates PEG10 expression by affecting histone methylation patterns.