Date published: 2025-10-17

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PCB Inhibitors

PCB inhibitors, short for polychlorinated biphenyl inhibitors, are a distinct class of chemical compounds known for their specific function in mitigating the toxic effects of polychlorinated biphenyls (PCBs). PCBs are a group of synthetic organic chemicals that were widely used in various industrial applications, such as coolants, insulating fluids, and lubricants, prior to their ban due to environmental and health concerns. The role of PCB inhibitors is primarily focused on environmental remediation and risk reduction. These inhibitors are designed to interact with PCBs in order to minimize their persistence, mobility, and toxicity in natural ecosystems. The chemical structures of PCB inhibitors are meticulously engineered to facilitate interactions with PCB molecules. These interactions can lead to several outcomes, including reducing the bioavailability of PCBs to organisms, promoting their degradation, or forming stable complexes that are less toxic. PCB inhibitors typically possess functional groups or chemical moieties that enable them to bind with PCB molecules through processes like chemical adsorption, complexation, or enzymatic degradation. This binding ability allows them to sequester or modify the PCBs, making them less harmful to both terrestrial and aquatic ecosystems. The development and utilization of PCB inhibitors represent a crucial strategy in the ongoing efforts to address the legacy of PCB contamination and protect the environment and public health from the adverse effects of these persistent organic pollutants.

Items 1 to 10 of 13 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Chlorothricin

34707-92-1sc-202098
1 mg
$179.00
1
(1)

Chlorothricin acts as a potent PCB by engaging in specific molecular interactions that disrupt cellular processes. Its unique structure allows for strong binding to target proteins, leading to altered conformational states. The compound exhibits notable reactivity due to its electrophilic nature, promoting rapid reaction kinetics with nucleophiles. Additionally, its hydrophobic properties enhance membrane permeability, facilitating its distribution and interaction within biological systems.

Aroclor 1254

11097-69-1sc-257096
50 mg
$140.00
1
(1)

Aroclor 1254 inhibits PCB metabolism by binding to the AhR receptor, preventing it from inducing cytochrome P450 enzymes. This reduces the activation of PCBs into more toxic metabolites.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol acts as a PCB inhibitor by modulating AhR signaling, reducing the expression of AhR-responsive genes involved in PCB-induced toxicity.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin inhibits PCB-induced inflammation and oxidative stress by suppressing NF-κB activation, a key pathway in mediating PCB toxicity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin attenuates PCB-induced oxidative stress by scavenging free radicals and inhibiting the production of reactive oxygen species (ROS).

N-Acetyl-L-cysteine

616-91-1sc-202232
sc-202232A
sc-202232C
sc-202232B
5 g
25 g
1 kg
100 g
$33.00
$73.00
$265.00
$112.00
34
(1)

NAC acts as a PCB inhibitor by replenishing glutathione levels, which helps detoxify PCBs and mitigate their harmful effects on cells.

Reserpine

50-55-5sc-203370
sc-203370A
1 g
5 g
$134.00
$406.00
1
(2)

Reserpine inhibits the release of norepinephrine and dopamine, reducing PCB-induced hyperactivity and behavioral disturbances in animals.

Trolox

53188-07-1sc-200810
sc-200810A
sc-200810B
sc-200810C
sc-200810D
500 mg
1 g
5 g
25 g
100 g
$37.00
$66.00
$230.00
$665.00
$1678.00
39
(1)

Trolox, a vitamin E derivative, functions as an antioxidant, mitigating PCB-induced oxidative stress and protecting cells from damage.

DL-α-Tocopherol

10191-41-0sc-294383
sc-294383A
sc-294383B
sc-294383C
5 g
25 g
100 g
500 g
$25.00
$51.00
$122.00
$320.00
3
(1)

Alpha-Tocopherol, a form of vitamin E, scavenges free radicals generated by PCB exposure, reducing oxidative damage and lipid peroxidation in cells.

β-Carotene

7235-40-7sc-202485
sc-202485A
sc-202485B
sc-202485C
1 g
25 g
50 g
5 kg
$68.00
$297.00
$502.00
$12246.00
5
(1)

β-Carotene, a precursor to vitamin A, has antioxidant properties that counteract PCB-induced oxidative stress and protect against lipid peroxidation.