Pax-6 Activators
Common Pax-6 Activators include, but are not limited to Retinoic Acid, all trans CAS 302-79-4, Forskolin CAS 66575-29-9, Dexamethasone CAS 50-02-2, Insulin CAS 11061-68-0 and GSK-3 Inhibitor XVI CAS 252917-06-9.
Pax-6 activators is a group of chemical compounds associated with the regulation of the Pax-6 gene. Pax-6, short for Paired Box Protein 6, is a highly conserved transcription factor that plays a crucial role in embryonic development, particularly in the development of the eye, brain, and other sensory organs. It is considered a master regulator of eye development in vertebrates. Mutations or dysregulation of Pax-6 can lead to a range of developmental abnormalities, including aniridia (absence of the iris) and various eye disorders. The study of Pax-6 activators focuses on understanding the mechanisms that control Pax-6 gene expression, which is essential for normal development and tissue differentiation.
Research into Pax-6 activators is essential for deciphering the intricate molecular mechanisms that govern early embryonic development and tissue differentiation. By identifying compounds that can modulate the expression of Pax-6, researchers can gain insights into interventions for developmental disorders that involve abnormalities in Pax-6 function. Activators of Pax-6 stimulate gene expression and it is essential to emphasize that these compounds are tools for studying the gene's regulation. Pax-6 activators contribute to the broader field of developmental biology, offering valuable insights into the genetic and molecular processes that underlie the formation of complex organs like the eye and brain.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Plays roles in eye and neural development; might influence PAX6 expression during embryonic development. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels, which might influence PAX6 expression in certain cell types. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Influences various cellular pathways; its effect on PAX6 expression in certain cells (like lens epithelial cells) is of interest. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Known to influence various cellular pathways; might modulate PAX6 expression during neurogenesis. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
An inhibitor of GSK3, which is involved in the Wnt signaling pathway. By modulating Wnt signaling, it might influence PAX6 expression in specific contexts. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of the TGF-β signaling pathway, which might influence PAX6 expression during specific developmental processes. | ||||||