Pax-6 Inhibitors
Common Pax-6 Inhibitors include, but are not limited to DAPT CAS 208255-80-5, Chetomin CAS 1403-36-7, Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-3-carboxylate CAS 24237-54-5, Cdk1/5 Inhibitor CAS 40254-90-8 and Staurosporine CAS 62996-74-1.
Pax-6 inhibitors belong to a chemical class designed to target the activity of the Pax-6 transcription factor. Pax-6, also known as paired box protein 6, is a critical developmental regulator that plays a significant role in the embryonic development of various tissues and organs, including the eyes, central nervous system, and pancreas. It functions as a transcription factor, binding to specific DNA sequences and regulating the expression of genes involved in cell differentiation, proliferation, and tissue morphogenesis.
By inhibiting Pax-6, researchers aim to manipulate its transcriptional activity and downstream gene expression patterns. This offers a way to investigate the intricate processes that Pax-6 governs during development and in various physiological contexts. The study of Pax-6 inhibitors contributes to understanding the molecular mechanisms underlying tissue formation, organogenesis, and cellular fate determination. These inhibitors provide valuable tools for dissecting the complex network of genes and signaling pathways influenced by Pax-6, shedding light on its contributions to embryonic development and tissue homeostasis.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
A γ-secretase inhibitor that might impact PAX-6 function through the Notch signaling pathway, affecting neural development. | ||||||
Chetomin | 1403-36-7 | sc-202535 sc-202535A | 1 mg 5 mg | $186.00 $674.00 | 10 | |
A fungal metabolite that may inhibit PAX-6-mediated transcriptional activation by interacting with its DNA-binding domain. | ||||||
Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-3-carboxylate | 24237-54-5 | sc-285521 sc-285521A | 5 g 25 g | $188.00 $525.00 | ||
An antifungal compound that could potentially impact PAX-6 function and gene expression, affecting neural development. | ||||||
Cdk1/5 Inhibitor | 40254-90-8 | sc-202094 sc-202094A sc-202094B | 1 mg 5 mg 10 mg | $62.00 $208.00 $374.00 | 2 | |
A potential PAX-6 inhibitor that could impact PAX-6-mediated transcriptional regulation, affecting neural development. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A kinase inhibitor that may indirectly affect PAX-6 expression by modulating kinase pathways related to neural development. | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | $33.00 $77.00 $120.00 | 14 | |
A sphingosine-1-phosphate receptor modulator that might affect PAX-6 expression and signaling pathways involved in neural development. | ||||||
Cryptotanshinone | 35825-57-1 | sc-280649 | 10 mg | $119.00 | 1 | |
A natural compound with potential inhibitory effects on PAX-6 expression, potentially affecting neural development. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
An inhibitor of DNA methyltransferases that could impact PAX-6 expression and epigenetic regulation in neural cells. | ||||||
BIX01294 hydrochloride | 1392399-03-9 | sc-293525 sc-293525A sc-293525B | 1 mg 5 mg 25 mg | $37.00 $112.00 $408.00 | ||
An inhibitor of G9a histone methyltransferase that may modulate PAX-6 expression through epigenetic regulation. | ||||||