PAT4 Activators
PAT4 Activators represent a selection of chemical compounds that have been identified to potentially enhance the activity of the PAT4 protein through various cellular mechanisms and signaling pathways. Forskolin, for instance, can elevate intracellular cAMP levels, potentially leading to the activation of protein kinase A (PKA), which may indirectly enhance the activity of PAT4 by creating a favorable cellular environment for its function in amino acid transport. Similarly, the direct activator of protein kinase C, PMA, could increase PAT4 activity by affecting membrane trafficking processes, ultimately impacting the insertion and functionality of amino acid transporters. Ionomycin, through its role as a calcium ionophore, has the potential to elevate intracellular calcium levels, which could activate calcium-dependent signaling pathways and, in turn, positively influence PAT4's role in amino acid transport.
Moreover, metabolic modulators such as Metformin and AICAR,PAT4 Activators represent a selection of chemical compounds that have been identified to potentially enhance the activity of the PAT4 protein through various cellular mechanisms and signaling pathways. Forskolin, for instance, can elevate intracellular cAMP levels, potentially leading to the activation of protein kinase A (PKA), which may indirectly enhance the activity of PAT4 by creating a favorable cellular environment for its function in amino acid transport. Similarly, the direct activator of protein kinase C, PMA, could increase PAT4 activity by affecting membrane trafficking processes, ultimately impacting the insertion and functionality of amino acid transporters. Ionomycin, through its role as a calcium ionophore, has the potential to elevate intracellular calcium levels, which could activate calcium-dependent signaling pathways and, in turn, positively influence PAT4's role in amino acid transport.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Adenylyl cyclase activator, Forskolin raises intracellular cAMP levels, which could enhance PAT4 activity by promoting a cellular environment that supports amino acid transport processes that PAT4 is involved in. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PKC activator, PMA indirectly increases PAT4 activity by modulating protein kinase C pathways, potentially affecting membrane trafficking and thus amino acid transporter insertion into the membrane, where PAT4 functions. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Calcium ionophore, Ionomycin elevates intracellular calcium, which may enhance PAT4 function by activating calcium-dependent signaling pathways that facilitate amino acid transport. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin receptor activator, Insulin can enhance PAT4 activity by promoting anabolic cellular processes, which includes upregulation of amino acid transport systems to meet increased metabolic demands. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
AMP-activated protein kinase (AMPK) activator, Metformin may increase PAT4 activity by altering cellular energy status and thus indirectly upregulating nutrient transporters including amino acid transporters. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
Sirtuin activator, NAD+ may enhance PAT4 function by modulating sirtuin activity, which can have downstream effects on cellular metabolism and nutrient transporter regulation. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AMPK activator, AICAR could enhance PAT4 activity by mimicking cellular energy depletion, which in turn may upregulate transporters such as PAT4 to increase amino acid uptake for energy production. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, LY294002 may indirectly enhance PAT4 activity by altering signaling pathways that regulate membrane protein trafficking, potentially affecting the localization and activity of amino acid transporters. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Sirtuin activator, Resveratrol may enhance PAT4 activity by affecting sirtuin-mediated cellular metabolic pathways, which could lead to the modulation of amino acid transporter systems. | ||||||