pan-Cytokeratin Activators
In the realm of cellular architecture, the class of pan-Cytokeratin activators emerges as a sophisticated ensemble of compounds, intricately influencing the functional dynamics of pan-Cytokeratin-an indispensable component within the cellular cytoskeleton. At the forefront of this molecular orchestration are Paclitaxel and Epothilone B, acting as stabilizers of microtubules. Their meticulous interplay extends beyond mere stabilization, actively promoting the assembly and organization of pan-Cytokeratin filaments within the cellular milieu. In contrast, Nocodazole, a disruptor of microtubule dynamics, introduces a controlled perturbation to the cytoskeletal equilibrium. By influencing the turnover and remodeling of the cytoskeleton, Nocodazole subtly impacts the arrangement of pan-Cytokeratin filaments, contributing to the dynamic restructuring of the cellular scaffold. Shifting the focus to actin dynamics, pivotal to cytoskeletal organization, compounds such as Jasplakinolide, Latrunculin A, and Phalloidin emerge as protagonists. Their intricate modulation of actin polymerization and stability intricately reverberates across the cytoskeletal canvas, indirectly shaping the arrangement of pan-Cytokeratin filaments within the broader architectural context.
Trichostatin A, a histone deacetylase inhibitor, assumes the role of a precision conductor in this molecular symphony. Through enhancement of gene transcription involved in pan-Cytokeratin synthesis, Trichostatin A intricately shapes the molecular repertoire, adding layers of sophistication to the structural harmony encoded within the cellular genome. Expanding the technical repertoire, Blebbistatin, Cytochalasin D, Y-27632, and Vinblastine each enact a specialized influence on cellular processes and cytoskeletal organization. Their indirect modulation of pan-Cytokeratin function contributes to the complex interplay of molecular signals, shaping the cellular landscape. In the realm of selective inhibition, HDAC6 Inhibitor emerges as a key regulator. By selectively inhibiting HDAC6, it modulates the acetylation status of α-tubulin, intricately influencing microtubule stability and, consequently, the overall cytoskeletal organization.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Promotes microtubule stabilization, leading to increased polymerization and bundling of cytoskeletal components, ultimately enhancing the assembly and function of pan-Cytokeratin filaments. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Mimics the action of paclitaxel by stabilizing microtubules, thereby indirectly promoting the organization and stability of pan-Cytokeratin filaments within cells. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Disrupts microtubule dynamics, influencing the organization of cytoskeletal components, including pan-Cytokeratin filaments, leading to increased turnover and remodeling of the cytoskeleton. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Enhances actin polymerization and stabilizes actin filaments, indirectly affecting pan-Cytokeratin by modulating the overall organization and dynamics of the cytoskeleton. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Binds to actin monomers, preventing their polymerization into filaments and indirectly impacting pan-Cytokeratin by disrupting the organization and stability of the cytoskeleton. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor, directly influencing chromatin structure and gene expression, potentially enhancing the transcription of genes involved in pan-Cytokeratin synthesis. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $179.00 $307.00 $455.00 $924.00 $1689.00 | 7 | |
Selective inhibitor of myosin II, indirectly influencing pan-Cytokeratin by affecting actomyosin contractility and modulating cellular tension, which can impact the organization of the cytoskeleton. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $229.00 | 33 | |
Binds to F-actin, stabilizing actin filaments and influencing the organization of the cytoskeleton, including pan-Cytokeratin filaments. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Disrupts actin polymerization, indirectly influencing pan-Cytokeratin by modulating the dynamics and organization of the cytoskeleton. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK, impacting actin cytoskeleton organization and indirectly affecting pan-Cytokeratin by modulating cellular processes such as adhesion and migration. | ||||||