PACS-2 Inhibitors
The chemical class of PACS-2 inhibitors consists of a wide array of compounds that indirectly influence the function of PACS-2 by targeting various cellular pathways and processes associated with it. These compounds do not interact directly with PACS-2 but exert their influence through modulation of signaling pathways, cellular trafficking, apoptosis, and other cellular mechanisms. The diversity in the mechanism of action of these compounds reflects the multifaceted role of PACS-2 in cellular physiology.
The inhibitors in this class range from kinase inhibitors to agents affecting cellular trafficking and calcium signaling. For example, compounds like Wortmannin and LY294002, which inhibit PI3K, can indirectly affect the signaling pathways where PACS-2 plays a role. Similarly, MEK inhibitors like U0126 and PD98059, by modulating the MAPK/ERK pathway, can influence cellular processes that are regulated by PACS-2. Inhibitors like Bafilomycin A1 and Tunicamycin disrupt cellular trafficking and protein folding processes, respectively, which are crucial for the proper functioning of PACS-2 in the cell. Additionally, compounds like Rapamycin and Staurosporine, which target mTOR and various protein kinases, respectively, demonstrate the broad spectrum of pathways that can indirectly influence PACS-2's role in the cell.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $96.00 $250.00 $750.00 $1428.00 | 280 | |
Inhibitor of the V-ATPase, can disrupt endosomal sorting and trafficking, potentially affecting PACS-2 related processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor, can affect the PI3K/Akt pathway, indirectly influencing PACS-2 activities. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, potentially affecting PACS-2 mediated processes by altering PI3K signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, could affect pathways involving PACS-2. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Another MEK inhibitor, potentially influencing PACS-2 through the MAPK/ERK pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor, may alter processes related to PACS-2 function in cell growth and survival. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A protein kinase inhibitor, could affect multiple signaling pathways associated with PACS-2. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant, can inhibit calcineurin, potentially influencing PACS-2 related signaling. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), potentially impacting calcium signaling related to PACS-2. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
A pan-caspase inhibitor, may affect apoptotic pathways associated with PACS-2. | ||||||