p57 Activators
Common p57 Activators include, but are not limited to Trichostatin A CAS 58880-19-6, Valproic acid sodium salt CAS 1069-66-5, D,L-Sulforaphane CAS 4478-93-7, Sodium Butyrate CAS 156-54-7 and Curcumin CAS 458-37-7.
p57 Activators is a class of chemical compounds that modulate the function or activity of p57, a cyclin-dependent kinase inhibitor involved in cell cycle regulation and development. P57, also known as CDKN1C, plays a pivotal role in controlling cell proliferation and differentiation by inhibiting cyclin-dependent kinases that drive cell cycle progression. The concept of p57 Activators suggests compounds that might influence the activity, expression, or stability of p57, impacting its ability to regulate the cell cycle and cellular differentiation processes.
p57 Activators interact with p57 or its associated partners, thereby affecting its regulatory functions. By modulating p57's activity, these compounds might influence the progression of the cell cycle, cellular proliferation, and differentiation events. The exploration of this concept would require thorough scientific investigation to understand the effects of these compounds on p57 and their implications for cell cycle regulation and development processes.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits HDACs, increases histone acetylation, and promotes an open chromatin state around the p57 gene promoter, potentially enhancing transcription. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Modulates cell cycle-related pathways, indirectly affecting p57 expression through its impact on cell cycle control and gene regulation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Acts as an HDAC inhibitor, increasing histone acetylation and potentially allowing for increased transcription of the p57 gene. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Influences cellular processes, possibly affecting p57 through indirect effects on signaling pathways related to cell cycle regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Inhibits HDACs, leading to histone hyperacetylation and increased accessibility of the p57 gene promoter for transcriptional activation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Affects signaling pathways involved in cell cycle regulation, potentially influencing p57 expression as part of its broader effects. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Activates AMPK and impacts cellular metabolism and signaling pathways, which might indirectly influence p57 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Modulates signaling pathways related to cell cycle control and gene expression, which could impact p57 levels. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Functions as an HDAC inhibitor, increasing histone acetylation and potentially promoting transcription of the p57 gene. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
Activates PPARγ, which influences gene expression. p57 might be indirectly impacted through PPARγ-mediated pathways. | ||||||