Date published: 2026-5-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

p15 Activators

Common p15 Activators include, but are not limited to Doxorubicin CAS 23214-92-8, Cisplatin CAS 15663-27-1, Trichostatin A CAS 58880-19-6, 5-Azacytidine CAS 320-67-2 and 5-Aza-2′-Deoxycytidine CAS 2353-33-5.

p15 Activators constitute a specific group of chemical compounds recognized for their capacity to modulate the activity of cyclin-dependent kinase inhibitor 2B (CDKN2B), also referred to as p15. This chemical class operates by interacting with and enhancing the signaling pathways associated with p15, a protein known for its role in cell cycle regulation and inhibition of cyclin-dependent kinases. p15 is acknowledged for its involvement in controlling cell cycle progression, cellular growth, and responses to various cellular cues.

p15 Activators exert their influence through specific molecular interactions that may amplify the downstream effects of p15-mediated signaling, contributing to the fine-tuning of cell cycle checkpoints, cellular proliferation, and differentiation. The intricate mechanisms through which p15 Activators impact p15-related pathways remain a focus of ongoing scientific exploration, offering insights into the complex interplay between cell cycle dynamics, growth control, and cellular responses to external signals. The specific ways in which this chemical class engages with p15 underscore its significance in unraveling the intricacies of cell cycle regulation and enhancing our understanding across various scientific domains.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-azacytidine demethylates DNA, allowing transcription factors to access the p15 promoter and activate its expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid induces p15 expression as cells undergo differentiation processes.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

An HDAC inhibitor that affects chromatin structure, potentially leading to increased p15 expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

Demethylates DNA, allowing transcription factors to access the p15 promoter and activate its expression.

Doxorubicin

23214-92-8sc-280681
sc-280681A
1 mg
5 mg
$176.00
$426.00
43
(3)

Doxorubicin induces DNA damage and activate p53, which then induces p15 expression as part of the DNA damage response.

Cisplatin

15663-27-1sc-200896
sc-200896A
100 mg
500 mg
$138.00
$380.00
101
(4)

Cisplatin induce DNA damage and activate p53, which then induces p15 expression as part of the DNA damage response.