OTTMUSG00000019010 Activators
The protein "ovary testis transcribed" (Gm15114) likely plays a significant role in reproductive biology, as indicated by its name. However, its specific functions and mechanisms of action remain largely uncharacterized, highlighting a common challenge in contemporary biology – understanding the roles of poorly defined proteins. In-depth studies, including biochemical assays and in vivo models, are essential to elucidate the interactions and effects of this protein within the cellular context.
The activation of Gm15114, as hypothesized based on general principles of cell signaling, suggests that it may be involved in a variety of cellular processes mediated by cyclic AMP (cAMP), protein kinase A (PKA), and other secondary messengers. These pathways are critical in regulating cell proliferation, apoptosis, or differentiation, potentially placing Gm15114 at a crucial juncture in reproductive or developmental processes. The chemicals listed, while not directly linked to Gm15114 in existing research, have been selected based on their known effects on these pathways, providing a starting point for further experimental investigations into the protein's function. This approach underscores the importance of comprehensive research to determine the precise role and biological significance of Gm15114. Such studies are not only crucial for understanding this specific protein but also for advancing our broader knowledge of cellular signaling and regulation, particularly in the context of reproductive biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Epinephrine, by engaging adrenergic receptors, increases cAMP via adenylate cyclase. Elevated cAMP might lead to PKA activation, which could phosphorylate and activate ovary testis transcribed protein, implicating it in adrenergic signaling mechanisms. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
IBMX inhibits phosphodiesterases, maintaining high cAMP levels. Higher cAMP can activate PKA, potentially leading to phosphorylation and activation of ovary testis transcribed protein, suggesting its involvement in cAMP-mediated responses. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
PGE2 activates EP receptors, leading to adenylate cyclase activation and cAMP increase. Elevated cAMP may activate PKA, potentially phosphorylating and activating ovary testis transcribed protein, indicating a role in prostaglandin-mediated signaling. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Caffeine, as a phosphodiesterase inhibitor, increases cAMP levels, potentially enhancing PKA activity. This might facilitate phosphorylation and activation of ovary testis transcribed protein, linking it to metabolic and stress response pathways. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram, a selective PDE4 inhibitor, elevates cAMP levels, potentially leading to PKA activation. PKA may then phosphorylate and activate ovary testis transcribed protein, suggesting its role in cognitive and inflammatory pathways. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin activates stress-activated protein kinases, which may indirectly influence ovary testis transcribed protein activity through stress response signaling pathways. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $103.00 $245.00 | 8 | |
Zaprinast inhibits PDE5, raising cGMP levels, which can enhance cAMP pathways, potentially leading to PKA activation and phosphorylation of ovary testis transcribed protein, suggesting a role in vascular functions. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
dbcAMP, a cAMP analog, directly activates PKA, potentially leading to phosphorylation and activation of ovary testis transcribed protein, emphasizing its role in cAMP-dependent signaling mechanisms. | ||||||
Milrinone | 78415-72-2 | sc-201193 sc-201193A | 10 mg 50 mg | $162.00 $683.00 | 7 | |
Milrinone, a PDE3 inhibitor, increases cAMP levels, potentially leading to PKA activation. This might result in phosphorylation and activation of ovary testis transcribed protein, suggesting a role in cardiac function. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, raises cAMP levels, potentially leading to PKA activation and phosphorylation of ovary testis transcribed protein, indicating its involvement in metabolic regulation. | ||||||