OTTMUSG00000018964 Activators
The "ovary testis transcribed" protein, as its name suggests, might be involved in reproductive biology, potentially playing roles in the development, function, or regulation of gonadal tissues. Given the speculative nature of its activators, understanding the protein's function requires elucidating its cellular and physiological context. The activation mechanisms proposed for the chemicals listed are based on their known effects on cellular signaling pathways, which indirectly influence a wide range of proteins, including those with as yet undefined functions like Gm15080.
Activation of Gm15080, or "ovary testis transcribed" protein, likely involves complex regulatory networks that integrate multiple signaling pathways. These pathways could include those regulated by cyclic AMP (cAMP), protein kinase A (PKA), and various stress or growth factors, which are influenced by the cellular context and external stimuli. The chemicals listed have been chosen for their roles in these pathways, suggesting that Gm15080's activation is closely tied to these broad cellular processes. This approach underscores the importance of understanding the protein's role within these networks to fully grasp its function and regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine acts on adrenergic receptors to increase cAMP levels via adenylate cyclase activation. The resultant PKA activation could phosphorylate and thus activate the ovary testis transcribed protein, potentially modulating reproductive or developmental processes. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
By inhibiting phosphodiesterases, caffeine increases cAMP levels, indirectly activating PKA. This could lead to the phosphorylation and activation of the ovary testis transcribed protein, suggesting a role in metabolic or stress response pathways. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX inhibits phosphodiesterases, leading to increased cAMP levels and PKA activation. This may phosphorylate and activate the ovary testis transcribed protein, implicating it in signal transduction pathways sensitive to intracellular cAMP levels. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 activates its G protein-coupled receptors, leading to adenylate cyclase activation and increased cAMP. This pathway may activate PKA, which could phosphorylate and activate the ovary testis transcribed protein, indicating a role in inflammation or immune responses. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
As a selective PDE4 inhibitor, rolipram increases cAMP levels, potentially activating PKA. PKA may then activate the ovary testis transcribed protein, suggesting its involvement in cognitive and inflammatory pathways. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin activates stress-activated protein kinases, which may indirectly activate the ovary testis transcribed protein through stress response or apoptosis-related signaling pathways. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $105.00 $250.00 | 8 | |
By inhibiting PDE5, zaprinast increases cGMP levels, which can cross-activate cAMP pathways, potentially leading to PKA activation and phosphorylation of the ovary testis transcribed protein, suggesting a role in vascular or reproductive functions. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
dbcAMP is a cAMP analog that directly activates PKA, potentially leading to direct phosphorylation and activation of the ovary testis transcribed protein, indicating its involvement in cAMP-dependent signaling pathways. | ||||||
Milrinone | 78415-72-2 | sc-201193 sc-201193A | 10 mg 50 mg | $165.00 $697.00 | 7 | |
Milrinone inhibits PDE3, increasing cAMP levels and potentially activating PKA, which could phosphorylate and activate the ovary testis transcribed protein, highlighting its role in cardiac and smooth muscle function. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, increases cAMP levels, potentially activating PKA. This could lead to phosphorylation and activation of the ovary testis transcribed protein, suggesting its role in cardiac and metabolic regulation. | ||||||