OTTMUSG00000015220 Inhibitors
The inhibition of the protein Gm13977 by these selected chemicals is based on the structural and functional properties of the protein. Protease inhibitors like PMSF, Iodoacetamide, E-64, Pepstatin A, Leupeptin, AEBSF, Bestatin, MG-132, and Lactacystin are chosen for their known mechanisms of inhibiting various proteases, which could be effective if Gm13977 shares similar functional characteristics.
Chelating agents such as EDTA and O-Phenanthroline are included for their potential to inhibit metalloproteins by removing essential metal cofactors, which would be effective if Gm13977 is a metalloprotein. Allicin is chosen for its ability to modify thiol-containing enzymes, potentially inhibiting Gm13977 if it contains reactive thiol groups. These proposed inhibitors for Gm13977 are based on general principles of protein biochemistry and the common functionalities of proteins. The actual inhibition of Gm13977 by these chemicals would require experimental validation, as these are theoretical selections based on known protein-inhibitor interactions.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Phenylmethylsulfonyl Fluoride | 329-98-6 | sc-3597 sc-3597A | 1 g 100 g | $50.00 $697.00 | 92 | |
PMSF could inhibit Gm13977 if it has serine protease-like activity, by irreversibly binding to the serine residue in its active site. | ||||||
α-Iodoacetamide | 144-48-9 | sc-203320 | 25 g | $255.00 | 1 | |
Iodoacetamide may inhibit Gm13977 by alkylating cysteine residues, assuming the protein has accessible cysteine residues crucial for its function. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
E-64 might inhibit Gm13977 if it functions similarly to cysteine proteases, by irreversibly binding to cysteine residues in its active site. | ||||||
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $73.00 $148.00 $316.00 $499.00 $1427.00 $101.00 | 19 | |
Leupeptin might inhibit Gm13977 if it is a serine or cysteine protease, by reversibly binding to its active site and impeding its proteolytic activity. | ||||||
AEBSF hydrochloride | 30827-99-7 | sc-202041 sc-202041A sc-202041B sc-202041C sc-202041D sc-202041E | 50 mg 100 mg 5 g 10 g 25 g 100 g | $65.00 $122.00 $428.00 $851.00 $1873.00 $4994.00 | 33 | |
AEBSF may inhibit Gm13977 by covalently modifying serine residues in the active site, provided the protein has serine protease-like functionality. | ||||||
Bestatin | 58970-76-6 | sc-202975 | 10 mg | $131.00 | 19 | |
Bestatin could inhibit Gm13977 if it functions as an aminopeptidase, by binding to its active site and preventing substrate access. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG-132 might inhibit Gm13977 if it is similar to proteasomes or calpains, by binding to and inhibiting its proteolytic activity. | ||||||
Lactacystin | 133343-34-7 | sc-3575 sc-3575A | 200 µg 1 mg | $188.00 $575.00 | 60 | |
Lactacystin could inhibit Gm13977 if it is a proteasome-like protein, by binding to its active site and blocking proteolysis. | ||||||
o-Phenanthroline monohydrate | 5144-89-8 | sc-202256 sc-202256A | 1 g 25 g | $43.00 $188.00 | 1 | |
O-Phenanthroline may inhibit Gm13977 if it is a metalloenzyme, by chelating its metal cofactors, thus inhibiting its activity. | ||||||
Allicin | 539-86-6 | sc-202449 sc-202449A | 1 mg 5 mg | $489.00 $1557.00 | 7 | |
Allicin might inhibit Gm13977 by interacting with thiol-containing enzymes, assuming Gm13977 has reactive thiol groups in its active site. | ||||||