OTTMUSG00000010207 Activators
Gm13040 is a gene that encodes for specific proteins, likely involved in distinct cellular processes or signaling pathways. Based on the general understanding of gene functions and protein interactions, it's reasonable to hypothesize that proteins encoded by Gm13040 play roles in critical cellular mechanisms. These proteins might be involved in signaling pathways, regulatory processes, or other essential cellular functions. Therefore, the activation of these proteins could significantly impact the cellular processes they regulate or contribute to. Activation mechanisms for proteins, including those encoded by Gm13040, are typically diverse, involving a variety of biochemical interactions and modifications.
Commonly, protein activation can occur through phosphorylation, a process where kinases add phosphate groups to proteins, changing their structure and activity. This post-translational modification is a fundamental method by which cells transmit signals and regulate protein function. Proteins can also be activated by binding specific ligands, causing conformational changes that lead to functional activation. In the case of Gm13040-encoded proteins, given the current lack of specific direct activators, the proposed chemicals in the table have been selected based on their known effects on cellular signaling pathways that could intersect with the activities of these proteins. These intersections are grounded in the understanding of cellular signaling networks. Understanding the activation of Gm13040-encoded proteins is crucial for comprehending their functional roles in cellular processes. This knowledge is vital for potential future applications in biomedical research and pharmacology. However, specific activation mechanisms for these proteins and their complete roles in cellular processes remain areas for future scientific exploration.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
Isobutylmethylxanthine (IBMX) inhibits phosphodiesterases, leading to elevated cAMP levels. This increase in cAMP can enhance protein kinase A (PKA) activity, which could phosphorylate and thereby activate proteins encoded by the Gm13040 gene. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2) interacts with EP receptors, increasing intracellular cAMP. This rise activates PKA, which could phosphorylate and activate proteins encoded by Gm13040, as PKA can target a broad spectrum of proteins for phosphorylation. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $75.00 $212.00 | 18 | |
Rolipram inhibits phosphodiesterase 4, increasing cAMP levels within cells. Elevated cAMP can enhance PKA activity, which may result in the phosphorylation and activation of proteins encoded by Gm13040. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Anisomycin, a protein synthesis inhibitor, activates stress-activated protein kinases (SAPKs/JNK). JNK activation can lead to phosphorylation of various proteins, potentially including those encoded by Gm13040, thereby contributing to their activation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor, which can lead to compensatory activation of alternative pathways that might activate proteins encoded by Gm13040, as cellular signaling networks often respond to pathway inhibition with complex compensatory mechanisms. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG modulates various signaling pathways, including MAPKs. These pathways can phosphorylate a range of substrates, potentially including proteins encoded by Gm13040, leading to their activation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin affects multiple signaling pathways, including PKC activation. PKC can phosphorylate a variety of proteins, and it's plausible that PKC, upon activation by curcumin, might phosphorylate and activate proteins encoded by Gm13040. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol influences several signaling pathways, including Sirtuin and AMPK. Activation of these pathways might lead to downstream activation of proteins encoded by Gm13040 through complex signaling interactions. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane activates various signaling pathways, including Nrf2. Activation of Nrf2 might influence the activity of proteins encoded by Gm13040 through changes in cellular redox status. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin activates TRPV1, leading to calcium influx and activation of downstream signaling pathways. These pathways could potentially influence the activity of proteins encoded by Gm13040. | ||||||