oogenesin 1 Inhibitors
Oogenesin 1 inhibitors represent a category of compounds that specifically target and inhibit the activity of oogenesin 1, a protein known to be highly expressed in oocytes during early stages of development. Oogenesin 1 belongs to the broader class of oocyte-specific proteins and has been implicated in the regulation of gene expression during oogenesis. This protein is thought to play a critical role in controlling the transcriptional activity of specific genes essential for the maturation and proper function of oocytes. Oogenesin 1 inhibitors are designed to interact with key domains of the oogenesin protein, potentially disrupting its interaction with other molecular partners or its ability to bind to DNA. Such inhibition could lead to altered gene expression profiles within the developing oocyte, influencing various aspects of cellular processes such as differentiation, cell cycle progression, and chromatin remodeling.
The design and synthesis of oogenesin 1 inhibitors generally involve structure-activity relationship (SAR) studies, aiming to fine-tune molecular features that optimize binding affinity and selectivity towards the oogenesin 1 protein. These inhibitors can take on various chemical forms, including small molecules, peptides, or even larger macromolecules. Studies in molecular biology and biochemistry have focused on identifying binding motifs on oogenesin 1, understanding the molecular mechanisms behind its function, and elucidating how inhibitors modulate its activity. Additionally, these inhibitors are useful tools in developmental biology research, providing a way to modulate oogenesin 1 activity and thus investigate its broader biological functions in oogenesis and early embryogenesis.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that can alter gene expression and could inhibit oogenesin 1 by changing the acetylation status of histones associated with the oogenesin 1 gene, leading to a change in the chromatin structure and subsequent repression of the protein's function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor that could inhibit oogenesin 1 by inhibiting the mTOR pathway, which is crucial for cell growth and proliferation. This could reduce the cellular resources necessary for oogenesin 1 function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that could inhibit oogenesin 1 by blocking the PI3K/Akt pathway, which is involved in several cellular processes including metabolism, growth, proliferation, and survival, potentially reducing the activity of oogenesin 1 as a consequence of these broader cellular effects. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a MEK inhibitor that could inhibit oogenesin 1 by inhibiting the MAPK/ERK pathway, which can control the activity of a variety of cellular functions that might be necessary for the proper functioning of oogenesin 1. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that could inhibit oogenesin 1 by blocking the p38 MAPK pathway, involved in stress responses, which could indirectly reduce the activity of oogenesin 1 if it is involved in cellular response to stress. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a PI3K inhibitor like LY294002, and it could inhibit oogenesin 1 by a similar mechanism of blocking the PI3K/Akt pathway, thereby potentially reducing the cellular processes necessary for oogenesin 1's activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that, like U0126, could inhibit oogenesin 1 by blocking the MAPK/ERK signaling pathway and therefore inhibiting the cellular functions that could be necessary for oogenesin 1 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that could inhibit oogenesin 1 by inhibiting the JNK signaling pathway, which is involved in controlling a range of cellular processes that could be necessary for oogenesin 1 function. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
ZM-447439 is an Aurora kinase inhibitor that could inhibit oogenesin 1 by inhibiting Aurora kinases which are involved in mitotic progression, this could indirectly affect oogenesin 1 if it is associated with cell cycle regulation. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Gefitinib is an EGFR inhibitor that could inhibit oogenesin 1 by blocking the EGFR signaling pathway, potentially reducing cellular proliferation and survival signals that might be necessary for oogenesin 1 function. | ||||||