Olfr867 Activators
Olfr867 is an olfactory receptor gene that plays a crucial role in the perception of specific odorants. It is primarily expressed in the olfactory sensory neurons, where it functions as a molecular sensor for various odor molecules. The activation of Olfr867 is essential for the initiation of olfactory signal transduction, which ultimately leads to the perception of specific odors. The activation of Olfr867 is achieved through various mechanisms involving specific chemical activators. These activators directly or indirectly influence the olfactory signaling pathway. Direct activators like Retinoic Acid and Forskolin interact with the receptor or downstream effectors to enhance its activity. Other chemicals, such as Guanosine Diphosphate and Guanine Nucleotide, modulate G-protein coupled signaling pathways, optimizing signal transduction.
Indirect activators like Ammonium Chloride and Lithium Chloride modify intracellular conditions, affecting the sensitivity and responsiveness of Olfr867 to odorants. Calcium ions and Diacylglycerol act as secondary messengers, facilitating signal transduction within the olfactory system. These chemicals collectively contribute to the functional activation of Olfr867, allowing it to effectively detect and respond to specific odor molecules in the environment.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid activates Olfr867 by binding to its receptor, leading to conformational changes that enhance its function within the olfactory signaling pathway. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin stimulates Olfr867 through the activation of adenylate cyclase, which increases intracellular cAMP levels, subsequently boosting the protein's activity. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Bromo-cAMP directly activates Olfr867 by mimicking cAMP's role, facilitating its interaction with downstream effectors in the signaling cascade. | ||||||
Guanosine 5′-diphosphate sodium salt hydrate (GDP) | 146-91-8 non-salt | sc-507402 | 10 mg | $645.00 | ||
Guanosine Diphosphate enhances Olfr867 activation by modulating G-protein coupled signaling pathways, promoting efficient signal transduction. | ||||||
1,2-Dioctanoyl-sn-glycerol | 60514-48-9 | sc-202397 sc-202397A | 10 mg 50 mg | $46.00 $249.00 | 2 | |
DAG activates Olfr867 by acting as a secondary messenger, initiating protein kinase C-mediated phosphorylation events that boost its function in olfactory signal transduction. | ||||||
Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
Calcium ions play a crucial role in Olfr867 activation by directly binding to the protein and inducing structural changes, thereby facilitating its odorant recognition process. | ||||||
Phorbol-12,13-dibutyrate | 37558-16-0 | sc-202285 | 1 mg | $122.00 | 3 | |
Phorbol 12,13-Dibutyrate activates Olfr867 through protein kinase C activation, which leads to enhanced signal transduction within the olfactory pathway. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $61.00 | 8 | ||
Ammonium Chloride indirectly activates Olfr867 by modifying intracellular pH levels, which influences the sensitivity and responsiveness of the olfactory receptor. | ||||||
Guanine | 73-40-5 | sc-211573 | 25 g | $21.00 | ||
Guanine nucleotide activates Olfr867 by directly interacting with G-protein signaling pathways, promoting efficient signal transduction and amplification. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin activates Olfr867 by increasing intracellular calcium levels, facilitating its involvement in odorant signal transduction processes. | ||||||