Olfr821 Activators
Olfr821 is an olfactory receptor protein predominantly found in the olfactory system of organisms. Its primary function is to detect and interact with specific odorant molecules, allowing the organism to perceive and discriminate various scents in its environment. Olfr821 serves as a molecular sensor, contributing significantly to the process of olfaction.
The activation of Olfr821 involves a highly coordinated series of events. When an odorant molecule binds to the receptor, it triggers a conformational change in Olfr821, initiating a signaling cascade. This cascade includes the activation of G-proteins, which leads to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels. Elevated cAMP levels, in turn, activate protein kinase A (PKA), phosphorylating downstream target proteins. These phosphorylation events ultimately result in the depolarization of olfactory sensory neurons, generating action potentials that convey the odorant information to the brain's olfactory cortex. In summary, Olfr821's activation is a precise and crucial process, enabling organisms to detect and distinguish various odors, enhancing their sensory experience and environmental awareness.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
8-CPT-cAMP | 93882-12-3 | sc-201569 sc-201569A | 20 mg 100 mg | $87.00 $316.00 | 19 | |
8-CPT-cAMP directly up-regulates Olfr821 by serving as a cAMP analog, promoting increased cAMP levels and heightened receptor activation. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol activates Olfr821 through the beta-adrenergic receptor, triggering cAMP production and subsequent enhancement of Olfr821 signaling. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Phorbol 12-myristate 13-acetate indirectly activates Olfr821 by modulating protein kinase C (PKC), which subsequently influences receptor signaling. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine indirectly activates Olfr821 through its GPCR, initiating downstream events that enhance receptor signaling and function. | ||||||
Prostaglandin F2α | 551-11-1 | sc-203219 | 1 mg | $88.00 | 1 | |
Prostaglandin F2alpha indirectly activates Olfr821 by binding to its GPCR and initiating intracellular events that enhance receptor signaling. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $34.00 $48.00 $300.00 $572.00 $1040.00 $2601.00 $4682.00 | 1 | |
Adenosine indirectly activates Olfr821 by binding to its GPCR and influencing intracellular pathways that amplify receptor activation responses. | ||||||
GABA | 56-12-2 | sc-203053 sc-203053A sc-203053B sc-203053C | 10 g 25 g 5 kg 10 kg | $64.00 $136.00 $459.00 $765.00 | 2 | |
GABA indirectly activates Olfr821 by binding to its GPCR and modulating downstream signaling pathways, ultimately enhancing receptor function. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine indirectly activates Olfr821 by binding to its respective GPCR, leading to downstream signaling events that enhance receptor function. | ||||||
ATP | 56-65-5 | sc-507511 | 5 g | $17.00 | ||
ATP indirectly activates Olfr821 by binding to its GPCR and initiating intracellular events that enhance receptor signaling and function. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine indirectly activates Olfr821 through its GPCR, initiating downstream signaling events that enhance receptor signaling and function. | ||||||