Chemical activators of Olfr435 play a crucial role in the sensory perception of specific odors. Benzaldehyde, for instance, binds to Olfr435, causing a conformational change that activates the G-protein coupled receptor. This activation leads to a cascade of signaling events that amplify the olfactory signal, enhancing the perception of odor. Acetophenone operates similarly, binding to Olfr435 and triggering an increase in intracellular cyclic AMP. This action activates protein kinase A, leading to signal transduction associated with the sensory perception of smell. Isoamyl Acetate serves as an agonist to Olfr435, inducing a structural change in the receptor that activates the G-protein, thereby initiating downstream effects that amplify the olfactory signal. Ethyl Butyrate specifically binds to Olfr435, triggering a pathway that increases intracellular calcium levels, crucial for odor signal transduction.
In addition to these, Methyl Salicylate and Cinnamaldehyde directly interact with Olfr435. Methyl Salicylate promotes a conformational change leading to G-protein activation, culminating in an increased sensory response. Cinnamaldehyde functions as an agonist, triggering the receptor's G-protein coupled signaling mechanism, enhancing the perception of related odors. Vanillin and Eugenol bind to Olfr435, activating the receptor and leading to a signaling cascade that amplifies the sensory perception of their respective odors. Limonene, Citral, Linalool, and Geraniol also play pivotal roles. Limonene triggers a conformational change in Olfr435, enhancing sensory response to limonene-like odors. Citral increases intracellular calcium level, essential for olfactory signal transduction. Linalool induces structural changes in Olfr435, increasing the sensory response, while Geraniol initiates a signaling cascade that enhances the perception of geraniol-related odors. Each of these chemicals activates Olfr435, leading to an enhanced and specific olfactory experience.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acetophenone | 98-86-2 | sc-239189 | 5 g | $20.00 | ||
Acetophenone, upon binding to Olfr435, causes an activation of the G-protein coupled receptor mechanism. This action leads to an increase in intracellular cyclic AMP, which in turn activates protein kinase A, resulting in signal transduction associated with the sensory perception of smell. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isopentyl acetate engages with Olfr435, functioning as an agonist. Its binding induces a change in the receptor's structure, enabling the activation of the G-protein. This activation initiates a series of downstream effects that amplify the olfactory signal, enhancing the sensory response to this specific odor molecule. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl Butyrate specifically binds to Olfr435, causing an activation of the G-protein coupled receptor. This binding triggers a signaling pathway that increases intracellular calcium levels, which plays a critical role in the transduction of olfactory signals, leading to an enhanced perception of related odors. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl Salicylate activates Olfr435 by binding to its olfactory receptor site, promoting a conformational change that initiates G-protein activation. This leads to a cascade of intracellular events, culminating in an increased sensory response to specific odorants. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde directly interacts with Olfr435, functioning as an agonist. This interaction triggers the receptor's G-protein coupled signaling mechanism, leading to the transduction of olfactory signals. This results in an enhanced sensory perception of odors associated with cinnamaldehyde. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin activates Olfr435 by binding to its receptor site, promoting the activation of the associated G-protein. This leads to a signaling cascade that amplifies the signal within olfactory sensory neurons, enhancing the sensory perception of vanilla-like odors. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol, upon binding to Olfr435, activates the G-protein coupled receptor mechanism. This interaction results in a series of intracellular events that enhance the perception of smell, particularly for odorants similar to eugenol. | ||||||
D-Limonene | 5989-27-5 | sc-205283 sc-205283A | 100 ml 500 ml | $82.00 $126.00 | 3 | |
Limonene engages Olfr435 as an agonist, triggering a conformational change in the receptor that activates the G-protein. This activation sets off a series of downstream events, amplifying the olfactory signal and enhancing the sensory response to limonene-like odors. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral binds to Olfr435, causing activation of the G-protein coupled receptor. This interaction initiates a signaling cascade that results in an increased intracellular calcium level, essential for the transduction of olfactory signals, thereby enhancing the perception of citral-related odors. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $46.00 $71.00 $108.00 | ||
Linalool interacts with Olfr435, activating the receptor by inducing a structural change. This activation leads to a series of intracellular events, culminating in an increased sensory response to linalool and similar odorants. | ||||||