OCM Activators
The chemical class of OCM Activators encompasses a range of compounds that exert their influence on the pathways associated with Oncomodulin indirectly. These chemicals primarily operate by modulating intracellular calcium levels or influencing calcium signaling pathways. Calcium is a pivotal element in cellular signaling, and its flux within the cell is critical for the activation and function of various calcium-binding proteins, including OCM.Compounds like Forskolin and cAMP elevate intracellular cAMP levels, which can modulate calcium signaling pathways integral to OCM activity. Ionophores like A23187 and Ionomycin directly increase intracellular calcium concentrations, thus potentially influencing OCM. Calcium channel blockers such as Nifedipine alter calcium influx, thereby impacting calcium-dependent cellular processes and possibly affecting OCM function.
Moreover, compounds affecting protein kinase C (PKC), such as PMA and Bisindolylmaleimide I, play a role in modulating calcium signals in cells. PKC is known for its role in calcium-dependent signaling, and its manipulation can indirectly influence pathways in which OCM is involved. Similarly, calmodulin inhibitors, by hindering calmodulin function, impact calcium signaling pathways, potentially affecting OCM activity. Additionally, factors like EGF and NGF, while not directly linked to OCM, modulate intracellular signaling cascades that may intersect with OCM-associated pathways. These compounds' influence extends to various cellular processes, including growth and differentiation, which are realms where OCM might play a role.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases intracellular cAMP levels by activating adenylate cyclase. Elevated cAMP can modulate calcium signaling pathways, which are crucial for OCM activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), which plays a role in modulating calcium signals in cells. PKC activation can indirectly influence OCM activity through calcium-dependent signaling pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A calcium ionophore that increases intracellular calcium concentrations, potentially affecting calcium-binding proteins like OCM. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
A calcium channel blocker that alters calcium influx in cells, thereby influencing calcium-dependent processes and potentially affecting OCM function. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $114.00 $175.00 $260.00 $362.00 $617.00 $1127.00 | ||
As a second messenger, cAMP is involved in several signaling pathways that can indirectly influence OCM through modulation of calcium signaling. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Another calcium ionophore, which increases intracellular calcium and can thereby influence OCM activity indirectly through calcium-mediated signaling pathways. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $26.00 $34.00 | 20 | |
While primarily an antibiotic, neomycin can influence phosphoinositide metabolism, indirectly affecting calcium signaling and potentially OCM activity. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $163.00 $300.00 $1642.00 | 18 | |
By inhibiting calmodulin, these compounds can alter calcium signaling pathways, potentially influencing OCM activity as both are calcium-binding proteins. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences several signaling pathways, including those involved in neurogenesis and cellular growth, potentially intersecting with OCM-related pathways. | ||||||