Date published: 2026-2-8

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OAS Antibodies

Santa Cruz Biotechnology features a diverse variety of OAS Antibodies for investigating 2',5'-oligoadenylate synthetases (OAS) in cellular processes. OAS Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). 2',5'-oligoadenylate synthetases (OAS) are key components in the innate immune response, particularly in detecting viral infections. The synthesis of 2',5'-oligoadenylates activates RNase L, which leads to viral RNA degradation and inhibits viral replication. Understanding 2',5'-oligoadenylate synthetases (OAS) function is vital for developing therapeutic strategies against viral diseases and advancing immune regulation knowledge. Researchers worldwide use OAS monoclonal antibodies to explore immune response mechanisms and viral defense pathways. Current investigations focus on how 2',5'-oligoadenylate synthetases (OAS) respond to different viral threats and regulate immune system activation. Ongoing studies examine the relationship between OAS activity and various autoimmune conditions. Santa Cruz Biotechnology monoclonal antibodies support cutting-edge research in virology and immunology, helping scientists uncover new insights into immune system function and viral defense mechanisms.

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OAS Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

OAS1 Antibody (E-2)

sc-515518mouse IgM κ342-363 (h)WB, IP, IF, ELISAh

new

(0)

OAS1 Antibody (F-3)

sc-374656mouse IgG1 κ337-364 (h)WB, IP, IF, ELISAh
9
(4)

Oas1a Antibody (C-5)

sc-374252mouse IgG1 κ337-369 (m)WB, IP, IF, ELISAm
1
(1)

Oas1a Antibody (C-8)

sc-365357mouse IgG1 κ308-367 (m)WB, IP, IF, ELISAm, r
2
(1)

Oas1a Antibody (E-2)

sc-365072mouse IgG2a κ308-367 (m)WB, IP, IF, IHC(P), ELISAm, r
7
(4)

OAS2 Antibody (G-9)

sc-271117mouse IgG2b κ706-735 (m)WB, IP, IF, IHC(P), ELISAm, r, h
10
(5)

OAS2 Antibody (C-1)

sc-374238mouse IgG1 κ1-180 (h)WB, IP, IF, ELISAh
3
(1)

OAS3 Antibody (D-7)

sc-398225mouse IgG1 κ2-29 (m)WB, IP, IF, ELISAm, r
3
(2)

OAS CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OAS1 CRISPR/Cas9 KO Plasmid (h)

sc-402414hGene KnockoutGFP0
(0)

OAS1 HDR Plasmid (h)

sc-402414-HDRhHomology Directed RepairPuromycin0
(0)

OAS3 Double Nickase Plasmid (m)

sc-434225-NICmGene KnockoutPuromycin0
(0)

OAS CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OAS1 CRISPR Activation Plasmid (h)

sc-402414-ACThGene ActivationPuro, Blast, Hygro0
(0)

OAS2 CRISPR Activation Plasmid (h)

sc-404302-ACThGene ActivationPuro, Blast, Hygro0
(0)

OAS3 CRISPR Activation Plasmid (h)

sc-405992-ACThGene ActivationPuro, Blast, Hygro0
(0)

OAS siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

OAS1 siRNA (h)

sc-61241hGene SilencingN/A
3
(0)

OAS1 shRNA Plasmid (h)

sc-61241-SHhGene SilencingPuromycin
3
(0)

OAS1 shRNA (h) Lentiviral Particles

sc-61241-VhGene SilencingPuromycin
3
(0)

Oas1a siRNA (m)

sc-150140mGene SilencingN/A0
(0)

Oas1a shRNA Plasmid (m)

sc-150140-SHmGene SilencingPuromycin0
(0)

Oas1a shRNA (m) Lentiviral Particles

sc-150140-VmGene SilencingPuromycin0
(0)

Oas1b siRNA (m)

sc-150141mGene SilencingN/A0
(0)

Oas1b shRNA Plasmid (m)

sc-150141-SHmGene SilencingPuromycin0
(0)

Oas1b shRNA (m) Lentiviral Particles

sc-150141-VmGene SilencingPuromycin0
(0)

Oas1c siRNA (m)

sc-150142mGene SilencingN/A0
(0)

Oas1c shRNA Plasmid (m)

sc-150142-SHmGene SilencingPuromycin0
(0)

Oas1c shRNA (m) Lentiviral Particles

sc-150142-VmGene SilencingPuromycin0
(0)

Oas1d siRNA (m)

sc-61242mGene SilencingN/A0
(0)

Oas1d shRNA Plasmid (m)

sc-61242-SHmGene SilencingPuromycin0
(0)

Oas1d shRNA (m) Lentiviral Particles

sc-61242-VmGene SilencingPuromycin0
(0)

Oas1e siRNA (m)

sc-150143mGene SilencingN/A0
(0)

Oas1e shRNA Plasmid (m)

sc-150143-SHmGene SilencingPuromycin0
(0)

Oas1e shRNA (m) Lentiviral Particles

sc-150143-VmGene SilencingPuromycin0
(0)

Oas1f siRNA (m)

sc-150144mGene SilencingN/A0
(0)

Oas1f shRNA Plasmid (m)

sc-150144-SHmGene SilencingPuromycin0
(0)

Oas1f shRNA (m) Lentiviral Particles

sc-150144-VmGene SilencingPuromycin0
(0)

Oas1g siRNA (m)

sc-150145mGene SilencingN/A0
(0)

Oas1g shRNA (m) Lentiviral Particles

sc-150145-VmGene SilencingPuromycin0
(0)

Oas1h siRNA (m)

sc-150146mGene SilencingN/A0
(0)

Oas1h shRNA Plasmid (m)

sc-150146-SHmGene SilencingPuromycin0
(0)

Oas1h shRNA (m) Lentiviral Particles

sc-150146-VmGene SilencingPuromycin0
(0)

OAS2 siRNA (h)

sc-61243hGene SilencingN/A0
(0)

OAS2 shRNA Plasmid (h)

sc-61243-SHhGene SilencingPuromycin0
(0)

OAS2 shRNA (h) Lentiviral Particles

sc-61243-VhGene SilencingPuromycin0
(0)

OAS2 siRNA (m)

sc-61244mGene SilencingN/A0
(0)

OAS2 shRNA Plasmid (m)

sc-61244-SHmGene SilencingPuromycin0
(0)

OAS2 shRNA (m) Lentiviral Particles

sc-61244-VmGene SilencingPuromycin0
(0)

OASL2 siRNA (m)

sc-150148mGene SilencingN/A0
(0)

OASL2 shRNA Plasmid (m)

sc-150148-SHmGene SilencingPuromycin0
(0)

OASL2 shRNA (m) Lentiviral Particles

sc-150148-VmGene SilencingPuromycin0
(0)

OAS3 siRNA (h)

sc-61245hGene SilencingN/A
1
(0)

OAS3 shRNA Plasmid (h)

sc-61245-SHhGene SilencingPuromycin
1
(0)

OAS3 shRNA (h) Lentiviral Particles

sc-61245-VhGene SilencingPuromycin
1
(0)

OAS3 siRNA (m)

sc-61246mGene SilencingN/A0
(0)

OAS3 shRNA Plasmid (m)

sc-61246-SHmGene SilencingPuromycin0
(0)

OAS3 shRNA (m) Lentiviral Particles

sc-61246-VmGene SilencingPuromycin0
(0)