Oas1a Antibody (C-8): sc-365357
- Oas1a Antibody (C-8) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 308-367 mapping at the C-terminus of Oas1a of mouse origin
- recommended for detection of Oas1a of mouse and rat origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-365357 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Oas1a Antibody (C-8) for WB applications. These reagents are now offered in bundles with Oas1a Antibody (C-8) (see ordering information below).
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Oas1a Antibody (C-8) is a mouse monoclonal IgG1 antibody that detects Oas1a in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Oas1a, a 400 amino acid protein, plays a crucial role in the cellular response to viral infections by functioning as a homotetramer that catalyzes the synthesis of 2′-, 5′- oligomers of adenosine, known as 2-5As. This process is vital as anti-Oas1a antibody (C-8) binds to double-stranded RNA and polymerizes ATP into PPP(A2′P5′A)N oligomers, which subsequently activate the latent RNase L enzyme. Once activated, RNase L cleaves single-stranded RNAs, leading to the inhibition of cellular protein synthesis and effectively impairing viral replication. The importance of Oas1a extends beyond antiviral properties; Oas1a monoclonal antibody (C-8) is also implicated in the regulation of cell growth, differentiation, and apoptosis, making Oas1a (C-8) antibody a significant factor in understanding the interferon response and its potential link to conditions such as diabetes mellitus. Oas1a (C-8) monoclonal antibody is an essential tool for researchers investigating these critical biological processes and the mechanisms of viral resistance.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oas1a Antibody (C-8) | sc-365357 | 200 µg/ml | $322.00 | |||
Oas1a Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-540330 | 200 µg Ab; 10 µg BP | $361.00 | |||
Oas1a Antibody (C-8): m-IgG1 BP-HRP Bundle | sc-542046 | 200 µg Ab; 20 µg BP | $361.00 | |||
Oas1a Antibody (C-8) X | sc-365357 X | 200 µg/0.1 ml | $322.00 |