Oas1a Antibody (C-5): sc-374252

Oas1a Antibody (C-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Oas1a protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Oas1a antibody (C-5) is available as a non-conjugated format. Oas1a, a member of the 2′-, 5′-oligoadenylate synthetase family, plays a crucial role in the cellular response to viral infections by synthesizing 2′-, 5′-oligomers of adenosine, which are essential for activating the latent RNase L enzyme. This activation leads to the degradation of single-stranded RNA, effectively inhibiting viral replication and cellular protein synthesis. Oas1a′s importance extends beyond antiviral properties; Oas1a is also involved in regulating cell growth, differentiation, and apoptosis, making Oas1a a significant player in various physiological processes. Additionally, Oas1a is implicated in the interferon response, which is vital for the immune system′s ability to combat viral pathogens. As a rodent homolog of human OAS1, Oas1a is instrumental in studying the mechanisms of host resistance to viral infections and has potential implications in understanding diseases such as diabetes mellitus.

The preferred Oas1a antibody is Oas1a Antibody (E-2): sc-365072.