Date published: 2025-11-28

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Nup188 Activators

The activators of Nup188 listed above are considered for their indirect effects on the protein's activity or expression. These compounds include natural substances such as EGCG and Curcumin. They operate through various mechanisms, impacting cellular signaling and metabolic pathways, which can create an environment conducive to the functions of Nup188 in nucleocytoplasmic transport. Forskolin and Sildenafil, affecting cAMP and cGMP signaling respectively, may influence cellular processes relevant to nuclear transport and indirectly affect Nup188. Curcumin and Resveratrol, known for their broad impact on cellular signaling, might modulate the activity or expression of Nup188.

Using these indirect activators is a strategic approach when direct activators of specific proteins like Nup188 are not well-established. It emphasizes the importance of understanding broader cellular contexts and signaling networks in regulating protein functions. Each compound, by modulating specific pathways, contributes to a cellular environment that may enhance or modulate the function of proteins such as Nup188, demonstrating the complex nature of protein regulation and the interconnectedness of cellular processes.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin raises cAMP levels, potentially influencing pathways that regulate nucleocytoplasmic transport and indirectly affecting Nup188.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG, with its antioxidant properties, could impact pathways related to nuclear transport, potentially affecting Nup188.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin affects various signaling molecules and pathways, potentially influencing Nup188 activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol modulates several signaling pathways, which may indirectly impact Nup188.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride, impacting GSK-3 signaling, could potentially influence Nup188.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$42.00
$62.00
$153.00
$255.00
$500.00
$30.00
37
(1)

Metformin, known for its effects on the AMPK pathway, may have indirect effects on Nup188.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Rapamycin, as an mTOR inhibitor, might affect Nup188 indirectly through its influence on cellular metabolism and transport pathways.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin, a flavonoid, could influence Nup188 through its effects on various signaling pathways.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Sodium butyrate, influencing gene expression, could indirectly affect Nup188.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$94.00
$173.00
$255.00
$423.00
26
(1)

Capsaicin affects various cellular signaling pathways, potentially impacting Nup188.