The activators of Nup188 listed above are considered for their indirect effects on the protein's activity or expression. These compounds include natural substances such as EGCG and Curcumin. They operate through various mechanisms, impacting cellular signaling and metabolic pathways, which can create an environment conducive to the functions of Nup188 in nucleocytoplasmic transport. Forskolin and Sildenafil, affecting cAMP and cGMP signaling respectively, may influence cellular processes relevant to nuclear transport and indirectly affect Nup188. Curcumin and Resveratrol, known for their broad impact on cellular signaling, might modulate the activity or expression of Nup188.
Using these indirect activators is a strategic approach when direct activators of specific proteins like Nup188 are not well-established. It emphasizes the importance of understanding broader cellular contexts and signaling networks in regulating protein functions. Each compound, by modulating specific pathways, contributes to a cellular environment that may enhance or modulate the function of proteins such as Nup188, demonstrating the complex nature of protein regulation and the interconnectedness of cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises cAMP levels, potentially influencing pathways that regulate nucleocytoplasmic transport and indirectly affecting Nup188. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, with its antioxidant properties, could impact pathways related to nuclear transport, potentially affecting Nup188. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin affects various signaling molecules and pathways, potentially influencing Nup188 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol modulates several signaling pathways, which may indirectly impact Nup188. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride, impacting GSK-3 signaling, could potentially influence Nup188. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $42.00 $62.00 $153.00 $255.00 $500.00 $30.00 | 37 | |
Metformin, known for its effects on the AMPK pathway, may have indirect effects on Nup188. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin, as an mTOR inhibitor, might affect Nup188 indirectly through its influence on cellular metabolism and transport pathways. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin, a flavonoid, could influence Nup188 through its effects on various signaling pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Sodium butyrate, influencing gene expression, could indirectly affect Nup188. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin affects various cellular signaling pathways, potentially impacting Nup188. | ||||||