Nrf2 Activators
Items 1 to 10 of 13 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
Oltipraz functions as a potent Nrf2 activator, engaging in specific interactions with Keap1, leading to the dissociation of the Nrf2-Keap1 complex. This disruption promotes Nrf2 translocation to the nucleus, where it binds to antioxidant response elements (AREs) in target genes. The compound's unique structural features enhance its binding affinity, influencing the expression of cytoprotective proteins and modulating oxidative stress responses through distinct signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane activates NRF2 by promoting its translocation to the nucleus and enhancing its binding to antioxidant response elements (AREs). It also inhibits Keap1, which leads to NRF2 stabilization. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin activates NRF2 by disrupting the Keap1-NRF2 interaction, leading to NRF2 stabilization and subsequent translocation to the nucleus to activate ARE-driven gene expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates NRF2 through multiple pathways, including inhibition of Keap1, increasing NRF2 protein levels, and promoting its nuclear translocation, thus enhancing ARE activation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin activates NRF2 by disrupting the Keap1-NRF2 interaction, allowing NRF2 to accumulate in the nucleus and activate the antioxidant response element. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG activates NRF2 by inhibiting Keap1, leading to NRF2 stabilization, nuclear translocation, and subsequent binding to AREs to induce antioxidant gene expression. | ||||||
Caffeic Acid | 331-39-5 | sc-200499 sc-200499A | 1 g 5 g | $31.00 $61.00 | 1 | |
Caffeic acid activates NRF2 by preventing its degradation through Keap1-dependent ubiquitination, leading to NRF2 accumulation in the nucleus and ARE activation. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin activates NRF2 by disrupting the Keap1-NRF2 interaction, allowing NRF2 to enter the nucleus and stimulate ARE-driven gene expression. | ||||||
(±)-Hesperetin | 520-33-2 | sc-202647 | 1 g | $46.00 | 4 | |
Hesperetin activates NRF2 by inhibiting Keap1, which results in NRF2 stabilization and nuclear translocation, ultimately leading to ARE activation. | ||||||
Carnosic acid | 3650-09-7 | sc-202520 sc-202520A | 10 mg 50 mg | $60.00 $165.00 | 6 | |
Carnosic acid activates NRF2 by inhibiting Keap1-mediated degradation of NRF2, allowing NRF2 to translocate to the nucleus and initiate ARE-dependent gene expression. | ||||||