Date published: 2026-3-17

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NPAS4 Activators

The chemical class of NPAS4 Activators encompasses a variety of compounds that can potentially stimulate or modulate the activity of NPAS4, primarily through their effects on signaling pathways and gene expression regulation. This class includes agents like Forskolin and Rolipram, which increase cAMP levels, potentially influencing transcription factors including NPAS4.

Curcumin, Resveratrol, Sulforaphane, EGCG, and Sodium Butyrate are compounds known for their neuroprotective, anti-inflammatory, and gene-regulatory effects, which could lead to the activation of NPAS4. HDAC inhibitors such as Valproic Acid and mood stabilizers like Lithium Chloride, by modulating gene expression and neuronal signaling, may also affect NPAS4 activity. Essential nutrients like Zinc known for their importance in brain function and neuroprotection, could potentially influence NPAS4. Caffeine, with its broad effects on neurotransmitter systems, is included for its potential to affect pathways related to NPAS4 activation.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

An activator of adenylate cyclase, leading to increased cAMP levels which can influence transcription factors, potentially including NPAS4.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$77.00
$216.00
18
(1)

A phosphodiesterase inhibitor that elevates cAMP levels, potentially affecting transcription factors like NPAS4.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Known for its neuroprotective and anti-inflammatory effects, curcumin can modulate various signaling pathways, potentially leading to the activation of NPAS4.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A polyphenol that can modulate various cellular pathways, potentially affecting NPAS4 activity.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

A compound found in cruciferous vegetables, known to modulate cellular stress responses and neuroprotective pathways, potentially influencing NPAS4 expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

A major component of green tea, known for its neuroprotective properties, which might influence NPAS4 expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A short-chain fatty acid that acts as a histone deacetylase inhibitor, potentially influencing gene expression including NPAS4.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

An HDAC inhibitor that can affect gene expression, potentially upregulating NPAS4.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Used in the treatment of bipolar disorder, it can modulate several signaling pathways, potentially influencing NPAS4 expression.

Zinc

7440-66-6sc-213177
100 g
$48.00
(0)

An essential mineral important for brain function, which might influence NPAS4 activity.