The chemical class of NPAS4 Activators encompasses a variety of compounds that can potentially stimulate or modulate the activity of NPAS4, primarily through their effects on signaling pathways and gene expression regulation. This class includes agents like Forskolin and Rolipram, which increase cAMP levels, potentially influencing transcription factors including NPAS4.
Curcumin, Resveratrol, Sulforaphane, EGCG, and Sodium Butyrate are compounds known for their neuroprotective, anti-inflammatory, and gene-regulatory effects, which could lead to the activation of NPAS4. HDAC inhibitors such as Valproic Acid and mood stabilizers like Lithium Chloride, by modulating gene expression and neuronal signaling, may also affect NPAS4 activity. Essential nutrients like Zinc known for their importance in brain function and neuroprotection, could potentially influence NPAS4. Caffeine, with its broad effects on neurotransmitter systems, is included for its potential to affect pathways related to NPAS4 activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylate cyclase, leading to increased cAMP levels which can influence transcription factors, potentially including NPAS4. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
A phosphodiesterase inhibitor that elevates cAMP levels, potentially affecting transcription factors like NPAS4. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known for its neuroprotective and anti-inflammatory effects, curcumin can modulate various signaling pathways, potentially leading to the activation of NPAS4. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol that can modulate various cellular pathways, potentially affecting NPAS4 activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound found in cruciferous vegetables, known to modulate cellular stress responses and neuroprotective pathways, potentially influencing NPAS4 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A major component of green tea, known for its neuroprotective properties, which might influence NPAS4 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid that acts as a histone deacetylase inhibitor, potentially influencing gene expression including NPAS4. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
An HDAC inhibitor that can affect gene expression, potentially upregulating NPAS4. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Used in the treatment of bipolar disorder, it can modulate several signaling pathways, potentially influencing NPAS4 expression. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
An essential mineral important for brain function, which might influence NPAS4 activity. | ||||||