NOXO1 Activators
NADPH Oxidase Organizer 1 (NOXO1) is a protein that organizes the formation of NADPH oxidase, an enzyme that generates reactive oxygen species (ROS). NOXO1 Activators represent a class of chemicals that can influence the function of NOXO1. These compounds can indirectly influence the function of NOXO1 through their effects on related cellular pathways.
Chemicals such as PMA, DPI, Apocynin, VAS2870, VAS3947, ML171, GKT137831, EGTA, Ebselen, Tempol, MitoQ, and NAC can potentially influence NOXO1 function through their effects on NADPH oxidase assembly, PKC mediated pathways, calcium-dependent signaling, and redox state modulation. The effects of these chemicals on NOXO1 function are context-dependent and may vary based on the cellular environment and other biochemical parameters.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Phorbol 12-myristate 13-acetate (PMA) is an activator of Protein Kinase C (PKC), potentially influencing NOXO1 through PKC mediated pathways. | ||||||
Thiazolyl Blue | 298-93-1 | sc-359848 sc-359848A sc-359848B sc-359848C | 1 g 5 g 25 g 100 g | $115.00 $275.00 $991.00 $3215.00 | 40 | |
Diphenyleneiodonium chloride (DPI) is a NADPH oxidase inhibitor that can indirectly influence NOXO1 by affecting the functionality of the complex that NOXO1 helps to assemble. | ||||||
Apocynin | 498-02-2 | sc-203321 sc-203321A sc-203321B sc-203321C | 1 g 10 g 100 g 500 g | $27.00 $68.00 $116.00 $360.00 | 74 | |
Apocynin is an inhibitor of NADPH oxidase assembly and can indirectly influence NOXO1 by affecting the formation of the complex that NOXO1 organizes. | ||||||
2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione | sc-501137 | 25 mg | $380.00 | |||
GKT137831 is a NOX1/4 inhibitor that can indirectly influence NOXO1 as NOXO1 is involved in the assembly of NOX1 and NOX4 complexes. | ||||||
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $21.00 $65.00 $120.00 $251.00 $815.00 | 23 | |
EGTA, a calcium chelator, can indirectly influence NOXO1 by affecting calcium-dependent signaling pathways, as calcium is required for the activation of NOX enzymes. | ||||||
TEMPOL | 2226-96-2 | sc-200825 | 1 g | $38.00 | 33 | |
Tempol is a superoxide dismutase mimetic and ROS scavenger that can indirectly influence NOXO1 by modifying the redox state of the cell. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
N-acetyl-L-cysteine (NAC) is a precursor of glutathione and a ROS scavenger that can indirectly influence NOXO1 by modifying the redox state of the cell. | ||||||